NCLEX Chronic Illness Practice Questions Related

Review NCLEX Chronic Illness Practice Questions related questions and content

Four clients are receiving tyrosine kinase inhibitors (TKIs). Which of these four clients should the nurse assess first?

  • A. Client with dry, itchy, peeling skin
  • B. Client with a serum calcium of $9.2 mg/dL
  • C. Client with a serum potassium of $2.8 mEq/L
  • D. Client with a weight gain of 0.5 pound (1.1 kg) in 1 day
Correct Answer: C

Rationale: Tyrosine kinase inhibitors (TKIs) target cancer cell signaling pathways but can cause electrolyte imbalances, among other side effects. A serum potassium of 2.8 mEq/L (normal 3.5-5.0 mEq/L) is critically low, risking cardiac arrhythmias or muscle dysfunction, making this client the priority for immediate assessment. Dry, itchy, peeling skin is a common TKI side effect, uncomfortable but not immediately life-threatening, warranting later attention for infection risk. A calcium level of 9.2 mg/dL is normal (8.5-10.2 mg/dL), requiring no urgent action. A 0.5-pound weight gain in a day is minor and less critical unless part of a pattern suggesting fluid retention. The nurse prioritizes the potassium imbalance due to its potential for rapid, severe consequences, reflecting oncology's emphasis on addressing physiological instability first.