Nokea
Furosemide is added to a treatment regimen for heart failure that includes digoxin. Monitoring for this combination includes:
- A. Hemoglobin
- B. Serum potassium
- C. Blood urea nitrogen
- D. Serum glucose
Correct Answer: B
Rationale: Furosemide's potassium loss can enhance digoxin toxicity, requiring potassium monitoring.
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A nurse working as a member of a research team is exploring the unique differences in drug response that each individual possesses based on his or her genetic makeup. This area of study is called:
- A. Pharmacotherapeutics
- B. Pharmacodynamics
- C. Pharmacoeconomics
- D. Pharmacogenomics
Correct Answer: D
Rationale: Pharmacogenomics is the area of study that includes mapping of the human genome. In the future, medical care and drug regimens may be personally designed based on a person's unique genetic makeup. Pharmacotherapeutics is the branch of pharmacology that deals with the use of drugs to treat, prevent, and diagnose disease. Pharmacodynamics involves how a drug affects the body. Pharmacoeconomics includes any costs involved in drug therapy.
Aminoglycosides work by irreversibly binding to the 30 ribosomal subunit.
- A. TRUE
- B. FALSE
Correct Answer: A
Rationale: Aminoglycosides irreversibly bind to the 30S ribosomal subunit, disrupting bacterial protein synthesis and leading to bactericidal effects.
A patient is being treated with isoniazid (INH), rifampin, and pyrazinamide in phase I of treatment for tuberculosis. The organism develops resistance to isoniazid. Which drug will the nurse anticipate the provider will order to replace the isoniazid?
- A. Ciprofloxacin (Cipro)
- B. Ethambutol (Myambutol)
- C. Kanamycin
- D. Streptomycin sulfate
Correct Answer: B
Rationale: Ethambutol replaces INH in phase I if resistance occurs; ciprofloxacin or kanamycin are less common first-line options. If there is bacterial resistance to isoniazid, the first phase may be changed to ethambutol, rifampin, and pyrazinamide.
Which of the following glucocorticosteroids are used for cerebral oedema:
- A. Triamcinolon
- B. Prednisolon
- C. Prednison
- D. Dexamethasone
Correct Answer: D
Rationale: Dexamethasone is preferred for cerebral edema due to its potent anti-inflammatory effects and minimal mineralocorticoid activity.
Which of the following is the indication for glucocorticoid prescribing?
- A. Cataract
- B. Prevention of respiratory distress
- C. Hypofunction of thyroid gland
- D. Hypocalcemia
Correct Answer: B
Rationale: Glucocorticoids are indicated to prevent respiratory distress, such as in preterm infants for lung maturation.