Nokea
Genetic testing for VCORC1 mutation to assess potential warfarin resistance is required prior to prescribing warfarin.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: VCORC1 testing is recommended but not required before prescribing warfarin; it's optional to guide dosing.
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B-Blockers are contra indicated in
- A. Hypertension
- B. Congestive cardiac failure
- C. Anxiety states
- D. Hyperthyroidis m
Correct Answer: B
Rationale: Beta-blockers worsen congestive heart failure.
Glibenclamide and chlorpropamide:
- A. Are well absorbed in Gl tract
- B. Increase release of endogenic insulin by pancreatic beta cells
- C. Is used as hormone replacement therapy for diabetes mellitus
- D. Is for internal use only
Correct Answer: B
Rationale: Glibenclamide and chlorpropamide increase endogenous insulin release from beta cells.
When assessing a patient before starting a drug regimen, why would the nurse consider it important to assess baseline kidney function?
- A. To anticipate adverse effects of drugs
- B. To determine patient's baseline electrolyte levels
- C. To determine patient's ability to excrete the drug
- D. To determine patient's ability to metabolize the drug
Correct Answer: C
Rationale: Kidney function determines drug excretion, critical for dosing and avoiding toxicity.
A nurse is providing information to a client who has early Parkinson's disease and a new prescription for pramipexole. The nurse should instruct the client to monitor for which of the following adverse effects of this medication?
- A. Hallucinations
- B. Increased salivation
- C. Diarrhea
- D. Discoloration of urine
Correct Answer: A
Rationale: Pramipexole, a dopamine agonist, can cause hallucinations , especially in Parkinson's patients.
Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:
- A. Substitutes for insulin usually secreted by the pancreas
- B. Decreases glycogenolysis by the liver
- C. Increases the release of insulin from beta cells
- D. Decreases peripheral glucose utilization
Correct Answer: B
Rationale: Metformin reduces hepatic glucose output (glycogenolysis), key in type 2 diabetes; it doesn't mimic insulin or increase release .