Nokea
Gram-positive spore-forming bacilli were extracted in anoxic environment from the patient's wound contaminated with soil. Cultivation on a blood-glucose agar resulted in growth of the colonies surrounded with hemolysis zone. What agent was extracted from the wound?
- A. Clostridium perfringens
- B. Clostridium botulinum
- C. Staphylococcus aureus
- D. Pseudomonas aeruginosa
Correct Answer: A
Rationale: The correct answer is A: Clostridium perfringens. Clostridium perfringens is a gram-positive spore-forming bacillus commonly found in soil. It produces hemolysis on blood agar, as described in the question. Clostridium botulinum is also a gram-positive spore-forming bacillus, but it does not typically cause hemolysis. Staphylococcus aureus is a gram-positive cocci, not a bacillus. Pseudomonas aeruginosa is a gram-negative bacterium, not a gram-positive spore-forming bacillus.
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The innate immune system is always working to protect the body and does not require any special preparation to stop infection:
- A. TRUE
- B. FALSE
- C. Both answers can be correct depending on the given situation
- D. None of the above
Correct Answer: A
Rationale: The correct answer is A: TRUE. The innate immune system is the body's first line of defense against infections and is always active, providing immediate protection without prior exposure to a specific pathogen. It includes physical barriers, such as skin and mucous membranes, and cellular components like phagocytes and natural killer cells. The innate immune response is nonspecific and rapid, providing a crucial initial defense against pathogens.
Choice B is incorrect because the innate immune system is always active, even without any prior exposure to pathogens. Choice C is incorrect because the innate immune system is consistently functioning to protect the body, regardless of the situation. Choice D is incorrect as the correct answer is A.
Which bacteria are capable of forming spores that help them survive in extreme conditions?
- A. Clostridium botulinum
- B. Bacillus anthracis
- C. Both A and B
- D. None of the above
Correct Answer: C
Rationale: The correct answer is C, both A and B. Clostridium botulinum and Bacillus anthracis are both capable of forming spores, which are a protective mechanism that allows them to survive harsh conditions. Clostridium botulinum causes botulism and forms spores in anaerobic environments, while Bacillus anthracis causes anthrax and forms spores in aerobic environments. Therefore, both choices A and B are correct. Choice D is incorrect as it contradicts the fact that both bacteria are capable of forming spores.
In order to prevent wound infection associated with surgical procedures a patient was given a synthetic antiprotozoan drug with a high activity against Helicobacter pylori. Specify this drug:
- A. Metronidazole
- B. Doxycycline hydrochloride
- C. Chingamin
- D. Acyclovir
Correct Answer: A
Rationale: The correct answer is A: Metronidazole. Metronidazole is a synthetic antiprotozoan drug with high activity against Helicobacter pylori, a bacterium that can cause wound infections. Metronidazole specifically targets anaerobic bacteria like H. pylori, making it effective in preventing wound infections.
Incorrect choices:
B: Doxycycline hydrochloride - Doxycycline is primarily used for bacterial infections, not protozoan infections like H. pylori.
C: Chingamin - Chingamin is not a commonly used drug for treating H. pylori infections or preventing wound infections.
D: Acyclovir - Acyclovir is an antiviral drug used to treat herpes infections, not bacterial or protozoan infections like H. pylori.
The catarrhal stage of the whooping cough is characterized by:
- A. Decrease in paroxysms of coughing
- B. Subsequent respiratory infection for many months after the onset of pertussis
- C. Uncontrollable coughing followed by a high pitched 'whoop' sound
- D. Mild respiratory symptoms (mild coughing, sneezing or a runny nose)
Correct Answer: D
Rationale: The correct answer is D because the catarrhal stage of whooping cough is characterized by mild respiratory symptoms such as mild coughing, sneezing, or a runny nose. During this stage, the cough may start to worsen but is not yet severe.
A: Incorrect - Decrease in paroxysms of coughing is not seen in the catarrhal stage; it occurs later in the paroxysmal stage.
B: Incorrect - Subsequent respiratory infection for many months after the onset of pertussis is not a characteristic of the catarrhal stage.
C: Incorrect - Uncontrollable coughing followed by a high pitched 'whoop' sound is typical of the paroxysmal stage, not the catarrhal stage.
Routes for transmission of nosocomial infections are
- A. air droplets and fecal-oral mechanism
- B. air droplets and contact mechanism
- C. parenteral mechanism
- D. all are correct
Correct Answer: D
Rationale: The correct answer is D because nosocomial infections can be transmitted through various routes, including air droplets, fecal-oral mechanism, contact mechanism, and parenteral mechanism. Air droplets can carry infectious agents through the air, while contact with contaminated surfaces or individuals can spread infections. Fecal-oral transmission occurs through ingesting contaminated food or water. Parenteral transmission involves the introduction of pathogens directly into the bloodstream. Therefore, all the options listed in D are correct routes for transmission of nosocomial infections. Choices A, B, and C are incorrect because they do not encompass all possible routes of transmission for nosocomial infections.