Hypothyroidism in children:
- A. Cretinism
- B. Myxoedema
- C. Graves disease
- D. Acromegaly
Correct Answer: A
Rationale: The correct answer is A: Cretinism. Cretinism is a condition of severe hypothyroidism during childhood, leading to stunted growth, intellectual disability, and physical deformities. Myxoedema refers to severe hypothyroidism in adults, not children. Graves disease is a form of hyperthyroidism, opposite of hypothyroidism. Acromegaly is a condition caused by excess growth hormone, not related to thyroid dysfunction. Therefore, Cretinism is the correct answer for hypothyroidism in children due to its specific characteristics and presentation.
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The only amine hormone to act like a steroid is ________.
- A. TH
- B. ACTH
- C. GH
- D. ADH
Correct Answer: A
Rationale: The correct answer is A: TH (Thyroid Hormone). TH is the only amine hormone that acts like a steroid because it is derived from an amino acid but functions similarly to steroid hormones by entering target cells and binding to intracellular receptors to regulate gene expression. ACTH, GH, and ADH are peptide hormones that do not act like steroids. ACTH stimulates the adrenal glands to produce cortisol, GH stimulates growth, and ADH regulates water balance in the body.
What is the speed of the wave?
- A. 1.5cm/s
- B. 3.0cm/s
- C. 300 cm/s
- D. 600 cm/s
Correct Answer: D
Rationale: The correct answer is D: 600 cm/s. The speed of a wave is determined by the formula speed = frequency x wavelength. Given that the frequency and wavelength are constant, the only way to increase the speed is to increase the frequency or the wavelength. Since both frequency and wavelength are fixed, the speed can only be increased by increasing both. Choice D, 600 cm/s, is double the speed of choice C, 300 cm/s, which indicates that both frequency and wavelength have been doubled, leading to the correct answer. Choices A and B are too low to be correct, as they are not consistent with the principles of wave speed calculation.
Which is a water soluble vitamin?
- A. D
- B. B12
- C. A
- D. K
Correct Answer: B
Rationale: The correct answer is B: B12. B12 is a water-soluble vitamin because it dissolves in water and can be easily excreted through urine if taken in excess. It plays a crucial role in red blood cell formation and neurological function. Vitamins D, A, and K are fat-soluble vitamins, meaning they require fat for absorption and are stored in the body's fat tissues, making it harder to excrete excess amounts. This is why B12 is the only water-soluble vitamin among the choices.
A girl presents with delayed puberty, absent secondary sexual characteristics, and primary amenorrhea. She also appears to be hypertensive and hypokalemia. Which of the following enzymes is increased if there is virilization of a person?
- A. 11b-Hydroxylase
- B. 17a-Hydroxylase
- C. 21b-Hydroxylase
- D. Pyruvate Kinase
Correct Answer: A
Rationale: The correct answer is A: 11b-Hydroxylase. In cases of virilization, increased androgen production occurs. 11b-Hydroxylase is involved in the synthesis of cortisol and aldosterone. When there is a deficiency in this enzyme, excess androgens are diverted towards the production of testosterone, leading to virilization. In contrast, choices B (17a-Hydroxylase) and C (21b-Hydroxylase) deficiencies result in decreased androgen production. Choice D, Pyruvate Kinase, is not related to steroid hormone synthesis. Therefore, the correct enzyme in this scenario is 11b-Hydroxylase.
The posterior pituitary stores and releases .
- A. prolactin and oxytocin
- B. oxytocin and antidiuretic hormone (ADH)
- C. ADH and growth hormone
- D. growth hormone and prolactin
Correct Answer: B
Rationale: The correct answer is B: oxytocin and antidiuretic hormone (ADH).
1. The posterior pituitary stores and releases oxytocin and ADH.
2. Oxytocin is responsible for uterine contractions and milk ejection.
3. ADH regulates water balance by controlling water reabsorption in the kidneys.
Therefore, B is the correct answer.
A, C, and D are incorrect because prolactin, growth hormone, and other hormones are not stored or released by the posterior pituitary.