Nokea
Idiosyncrasy is:
- A. A genetically determined abnormal reaction to drugs
- B. A characteristic toxic effect at therapeutic doses
- C. An altered physiological state produced by repeated drug use
- D. An immunologically mediated reaction
Correct Answer: A
Rationale: Idiosyncrasy is a genetically determined unusual response to a drug, e.g., G6PD deficiency with primaquine.
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Amphetamine is used in
- A. Narcolepsy
- B. Psychosis
- C. Anxiety disorders
- D. Obsessive compulsive neurosis
Correct Answer: A
Rationale: Amphetamine treats narcolepsy by promoting wakefulness.
A nurse is teaching a client who has a new prescription for Nitroglycerin transdermal patch for Angina Pectoris. Which of the following instructions should the nurse include?
- A. Remove the patch each evening.
- B. Cut each patch in half if angina attacks are under control.
- C. Take off the nitroglycerin patch for 30 min if a headache occurs.
- D. Apply a new patch every 48 hr
Correct Answer: A
Rationale: Removing the patch nightly prevents tolerance to nitroglycerin.
The nurse administers amoxicillin 500 mg. The half-life of this drug is approximately 1 hour. At what point would the drug level in the body be 62.5 mg if the drug was not administered again?
- A. 1 hours after the original dose
- B. 2 hours after the original dose
- C. 3 hours after the original dose
- D. 4 hours after the original dose
Correct Answer: C
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to one-half of the peak level it previously achieved. At a dose of 500 mg the drug level would be 250 mg in 1 hour, 125 mg in 2 hours, 62.5 mg in 3 hours, and 31.25 mg in 4 hours so the correct answer is 3 hours.
The nurse is helping a client review a prescription from the health care provider. When examining the prescription, which of the following would the nurse expect to find documented?
- A. Name of the drug
- B. Dosage of the drug
- C. Route of drug administration
- D. All the above
Correct Answer: D
Rationale: The prescription must contain the client's name, the name of the drug, the dosage, the method and times of administration, and the signature of the licensed health care provider prescribing the drug.
A patient is prescribed a buccal medication. The nurse would instruct the patient to place the drug at which location?
- A. Under the tongue
- B. Against the cheek mucous membrane
- C. Inside the rectum
- D. At the back of the tongue
Correct Answer: B
Rationale: Buccal drugs are placed in the mouth against the mucous membranes of the cheek in either the upper or lower jaw. Sublingual medications are placed under the tongue. Rectal suppositories are inserted into the rectum. Oral medications are placed at the back of the tongue.