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If a portion of a strand of DNA bases reads 5' AGCTAGCGT 3', what would the sequence of bases on the complementary strand read?

  • A. 3' AGCTAGCGT 5'
  • B. 5' UCGAUCGCA 3'
  • C. 3' TCGATCGCA 5'
  • D. 5' TCGUTCGCU 3'
Correct Answer: C

Rationale: To determine the sequence of bases on the complementary DNA strand, you must apply the base pairing rules: adenine (A) pairs with thymine (T) and cytosine (C) pairs with guanine (G). The given original sequence is 5' AGCTAGCGT 3'. Consequently, the complementary strand will read 3' TCGATCGCA 5'. Each base on one strand corresponds with its complementary base on the other strand, forming a sequence that complements the original one.