Nokea
In autism:
- A. Social interaction is normal
- B. Dopamine levels are reduced
- C. Genetic factors may play a role in aetiology
- D. Methylphenidate is used with benefit
Correct Answer: C
Rationale: Genetic factors may play a role in aetiology: Autism spectrum disorder (ASD) has a strong genetic component, with numerous genes contributing to its development, although environmental factors may also play a role.
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Which of the following skills would be expected of a 7-month-old infant but not of a 5-month-old infant?
- A. Crawls
- B. Smiles socially
- C. Controls bowel and bladder
- D. Sits unsupported
Correct Answer: D
Rationale: A 7-month-old can typically sit unsupported, while a 5-month-old cannot. Crawling and social smiling develop earlier, and bowel control is not expected at this age.
What is cardiac power output (CPO) in a patient with acute anterior wall ST-elevation myocardial infarction and left ventricular failure? His mean arterial pressure was 60 mm Hg and cardiac output calculated on echo was 2.91l min−1.
- A. 0.48
- B. 0.38
- C. 0.58
- D. 0.68
Correct Answer: C
Rationale: Cardiac power output is calculated as (MAP × cardiac output) / 451. For the given values, the correct calculation gives a value of 0.58.
A child has an elevated antistreptolysin O (ASO) titer. Which combination of symptoms, in conjunction with this finding, would confirm a diagnosis of rheumatic fever?
- A. Subcutaneous nodules and fever
- B. Painful, tender joints, and carditis
- C. Erythema marginatum and arthralgia
- D. Chorea and elevated sedimentation rate
Correct Answer: B
Rationale: The presence of two major Jones criteria would indicate a high probability of rheumatic fever.
The following drugs induce hepatic enzymes:
- A. Rifampicin
- B. Phenobarbitone
- C. Cimetidine
- D. Erythromycin
Correct Answer: A
Rationale: Rifampicin is known to induce hepatic enzymes, which can increase the metabolism of other drugs and reduce their efficacy.
Renal childhood diseases responsible for chronic hypertension include
- A. nephrotic syndrome
- B. hemolytic uremic syndrome
- C. acute tubular necrosis
- D. congenital dysplastic kidney
Correct Answer: D
Rationale: Congenital dysplastic kidney is a common cause of chronic hypertension in children.