In normal neonates:
- A. Extracellular fluid volume exceeds intracellular fluid volume
- B. In a term baby, plasma calcium levels exceed that of the mother
- C. Clamping the umbilical cord after cessation of cord pulsations increases the blood volume by 20% in the baby
- D. There are two arteries and one vein in the umbilical cord
Correct Answer: A
Rationale: In neonates, extracellular fluid volume is greater than intracellular fluid volume, reflecting the transition from intrauterine to extrauterine life.
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What are FOUR possible causes of left axis deviation in a newborn with features of Trisomy 21?
- A. AVSD
- B. Tricuspid atresia
- C. Pulmonary atresia with intact ventricular septum
- D. Mechanical shift
Correct Answer: A
Rationale: AVSD is a common congenital heart defect associated with Trisomy 21 and can lead to left axis deviation seen on ECG.
List FOUR differential diagnoses aside from aortic coarctation for a two-week old infant presenting with tachypnea and poor femoral pulses.
- A. Tachycardia induced cardiomyopathy
- B. Critical aortic stenosis
- C. Dilated cardiomyopathy
- D. Myocarditis
Correct Answer: A
Rationale: Differential diagnoses in such cases can include non-structural heart conditions like tachycardia induced cardiomyopathy, which affects the heart's ability to pump effectively.
Cantwell criteria is used to diagnose
- A. Congenital tuberculosis
- B. Congenital syphilis
- C. Congenital rubella
- D. None of the above
Correct Answer: B
Rationale: The Cantwell criteria are used to diagnose congenital syphilis, based on clinical and laboratory findings.
Increased fetal haemoglobin is seen in:
- A. Haemoglobin H disease
- B. β-thalassaemia major
- C. Fanconi's anaemia
- D. Pyruvate kinase deficiency
Correct Answer: B
Rationale: Increased fetal haemoglobin (HbF) is a compensatory mechanism in β-thalassaemia major to counteract the reduced production of adult haemoglobin (HbA).
The child becomes unresponsive. The most likely underlying lesion is
- A. cardiomyopathy
- B. anomalous coronary artery
- C. tetralogy of Fallot
- D. constipation
Correct Answer: C
Rationale: Tetralogy of Fallot can cause hypoxic spells leading to unresponsiveness.