Nokea
In systemic mastocytosis:
- A. Areas of depigmentation occur
- B. Intermittent flushing is seen
- C. IgE levels are high
- D. Is relieved by aspirin
Correct Answer: B
Rationale: Intermittent flushing is a recognized symptom of systemic mastocytosis due to the release of histamine and other chemicals from mast cells.
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All of the following reduces intensity of first heart sound (S1) except
- A. Mechanical ventilation
- B. Calcific mitral stenosis
- C. Short PR interval
- D. LV dysfunction
Correct Answer: B
Rationale: Calcific mitral stenosis typically increases the intensity of the first heart sound (S1).
Acetazolamide:
- A. Is used in the management of renal tubular acidosis
- B. Causes hypokalaemia
- C. Is usually given intravenously
- D. Inhibits the action of carbonic anhydrase
Correct Answer: D
Rationale: Inhibits the action of carbonic anhydrase: Acetazolamide works by inhibiting carbonic anhydrase, reducing the reabsorption of bicarbonate in the kidneys and helping with conditions like glaucoma, metabolic alkalosis, and altitude sickness.
Coxsackie viruses are implicated in:
- A. Herpangina
- B. Dermatitis herpetiformis
- C. Meningitis
- D. Orchitis
Correct Answer: A
Rationale: Coxsackie viruses are a common cause of herpangina. They can also cause meningitis and orchitis, but dermatitis herpetiformis is not associated with Coxsackie viruses.
Severe pulmonary valve stenosis is defined as a peak gradient of
- A. >40 mm Hg
- B. >45 mm Hg
- C. >50 mm Hg
- D. >55 mm Hg
Correct Answer: C
Rationale: Severe pulmonary valve stenosis is generally defined as a peak gradient >50 mm Hg.
Common diseases presenting as a rash in infancy are:
- A. Measles
- B. Parvovirus B 19 infection
- C. Leukaemia
- D. Lymphoma
Correct Answer: A
Rationale: Measles