Nokea
In the most common type of CAH:
- A. Autosomal dominant transmission occurs
- B. II -Hydroxylase is deficient
- C. Hypertension is seen
- D. 17-OH progesterone is increased
Correct Answer: D
Rationale: 17-OH progesterone is increased: In congenital adrenal hyperplasia (CAH), the most common form is 21-hydroxylase deficiency, leading to increased 17-hydroxyprogesterone levels.
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Which is a common, serious complication of rheumatic fever?
- A. Seizures
- B. Cardiac arrhythmias
- C. Pulmonary hypertension
- D. Cardiac valve damage
Correct Answer: D
Rationale: Cardiac valve damage is the most significant complication of rheumatic fever. Seizures, cardiac arrhythmias, and pulmonary hypertension are not common complications of rheumatic fever.
The following antibodies are seen in the conditions mentioned:
- A. Anti-endomysial antibodies in coeliac disease
- B. Anti-insulin receptor antibodies in diabetes mellitus
- C. Anti-epidermal antibodies in vitiligo
- D. Anti-acetylcholine receptor antibodies in spinal muscular atrophy
Correct Answer: A
Rationale: Anti-endomysial antibodies are specifically associated with coeliac disease, making (a) the correct answer. The other options are incorrect as they describe antibodies associated with different conditions.
A characteristic sign of hypercalcaemia is:
- A. Trousseau's sign
- B. Chvostek's sign
- C. Homan's sign
- D. Kussmaul's sign
Correct Answer: A
Rationale: Trousseau's sign, which involves muscle spasms when a blood pressure cuff is inflated, is a common indicator of hypocalcemia, not hypercalcemia.
What are FOUR absolute contraindications for cardiac transplantation?
- A. Active infection
- B. Ongoing malignancy
- C. Medical non-compliance
- D. Drug abuse
Correct Answer: D
Rationale: These are absolute contraindications for cardiac transplantation due to the risks of infection, poor outcomes, and non-compliance.
Bronchoconstriction is a recognised side effect of:
- A. Captopril
- B. Salbutamol
- C. Ibuprofen
- D. Paracetamol
Correct Answer: B
Rationale: Salbutamol can cause bronchoconstriction in some cases due to its paradoxical effect, especially if overused or misused.