Inclisiran used in the treatment of dyslipidemia is chemically a
- A. Synthetic RNA
- B. Synthetic histone
- C. Synthetic DNA
- D. Synthetic mitochondria
Correct Answer: A
Rationale: Inclisiran is a synthetic RNA molecule used to lower cholesterol levels.
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A psychiatric referral is warranted in a preschool child with the following:
- A. Night terrors
- B. Separation anxiety
- C. Scared of ghosts
- D. Masturbation
Correct Answer: B
Rationale: Separation anxiety in a preschool child, especially if it is severe and persistent, may warrant a psychiatric referral to assess for anxiety disorders.
The nurse is conducting a staff in-service on congenital heart defects. Which structural defect constitutes tetralogy of Fallot?
- A. Pulmonic stenosis, ventricular septal defect, overriding aorta, right ventricular hypertrophy
- B. Aortic stenosis, ventricular septal defect, overriding aorta, right ventricular hypertrophy
- C. Aortic stenosis, atrial septal defect, overriding aorta, left ventricular hypertrophy
- D. Pulmonic stenosis, ventricular septal defect, aortic hypertrophy, left ventricular hypertrophy
Correct Answer: A
Rationale: Tetralogy of Fallot has these four characteristics: pulmonic stenosis, ventricular septal defect, overriding aorta, and right ventricular hypertrophy. There is pulmonic stenosis but not atrial stenosis in tetralogy of Fallot. Right ventricular hypertrophy, not left ventricular hypertrophy, is present in tetralogy of Fallot. Tetralogy of Fallot has right ventricular hypertrophy, not left ventricular hypertrophy, and an atrial septal defect, not aortic hypertrophy.
The following are true about water excretion:
- A. It is influenced by the proximal tubule
- B. It is influenced by vasopressin
- C. It depends on erythropoietin
- D. It is influenced by the ascending limb of the loop of Henle
Correct Answer: B
Rationale: It is influenced by vasopressin: Vasopressin (ADH) regulates water reabsorption in the kidneys, primarily by acting on the collecting ducts, enhancing water retention in response to dehydration.
Severe pulmonary valve stenosis is defined as a peak gradient of
- A. >40 mm Hg
- B. >45 mm Hg
- C. >50 mm Hg
- D. >55 mm Hg
Correct Answer: C
Rationale: Severe pulmonary valve stenosis is generally defined as a peak gradient >50 mm Hg.
Medical treatment of myasthenia gravis includes:
- A. Thymectomy
- B. Physostigmine
- C. Edrophonium
- D. Anticholinergic agents
Correct Answer: C
Rationale: Edrophonium: Edrophonium is used in the diagnosis and short-term treatment of myasthenia gravis as it improves neuromuscular transmission by inhibiting acetylcholinesterase.
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