Kasey fractured his ankle in two places and is asking for medication for his pain. The appropriate first-line medication would be:
- A. Ibuprofen (Advil)
- B. Acetaminophen with hydrocodone (Vicodin)
- C. Oxycodone (Oxycontin)
- D. Oral morphine (Roxanol)
Correct Answer: B
Rationale: Acetaminophen with hydrocodone is suitable for moderate-to-severe fracture pain.
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The client with small cell lung cancer is being treated with etoposide (VePesid). The nurse who is assisting in caring for the client during its administration understands that which side effect is specifically associated with this medication?
- A. Alopecia
- B. Chest pain
- C. Pulmonary fibrosis
- D. Orthostatic hypotension
Correct Answer: D
Rationale: A side effect specific to etoposide is orthostatic hypotension. The client's blood pressure is monitored during the infusion. Hair loss occurs with nearly all the antineoplastic medications. Chest pain and pulmonary fibrosis are unrelated to this medication.
Tetracycline needs to be given on an empty stomach because it chelates with:
- A. Calcium
- B. Magnesium
- C. Iron
- D. All of the above
Correct Answer: D
Rationale: Tetracycline forms insoluble complexes with divalent and trivalent cations (calcium, magnesium, iron), reducing absorption when taken with food containing these elements.
Which of the following is CORRECT about aspirin poisoning?
- A. Is rarely seen in cases of chronic use
- B. It does not affect body temperature
- C. It is treated by administration of intravenous sodium bicarbonate
- D. The earliest sign is hypoventilation
Correct Answer: C
Rationale: Sodium bicarbonate enhances aspirin excretion by alkalinizing urine.
Janice has elevated LDL, VLDL, and triglyceride levels. Niaspan, an extended-release form of niacin, is chosen to treat her hyperlipidemia. Due to its metabolism and excretion, which of the following laboratory results should be monitored?
- A. Serum alanine aminotransferase
- B. Serum amylase
- C. Serum creatinine
- D. Phenylketonuria
Correct Answer: A
Rationale: Niacin can cause hepatotoxicity, requiring ALT monitoring.
Off-label prescribing is:
- A. Regulated by the U.S. Food and Drug Administration
- B. Illegal by NPs in all states (provinces)
- C. Legal if there is scientific evidence for the use
- D. Regulated by the Drug Enforcement Administration
Correct Answer: C
Rationale: Off-label prescribing is legal with scientific support , not FDA-regulated , universally illegal , or DEA-controlled .
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