Human Reproductive System Related

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Levels of transcortin are elevated in a pregnant woman. Which of the following laboratory findings would be expected in this patient?

  • A. Increased total (protein-bound plus free) plasma cortisol concentration
  • B. Increased free (non–protein-bound) plasma cortisol concentration
  • C. Decreased total plasma cortisol concentration
  • D. Decreased free plasma cortisol concentration
Correct Answer: A

Rationale: Rationale: Elevated levels of transcortin in a pregnant woman lead to an increase in total plasma cortisol concentration. Transcortin binds to cortisol, increasing its total concentration but reducing the amount of free (non-protein-bound) cortisol. Choice A is correct as total cortisol concentration increases due to transcortin binding. Choices B and D are incorrect as free cortisol concentration decreases. Choice C is incorrect as total cortisol concentration is elevated, not decreased.