Lispro is an insulin analogue produced by recombinant DNA technology. Which of the following statements about this form of insulin is NOT true?
- A. Optimal time of preprandial injection is 15 minutes
- B. Duration of action is increased when the dose is increased
- C. It is compatible with neutral protamine Hagedorn insulin
- D. It has no pronounced peak
Correct Answer: B
Rationale: Lispro's duration is fixed (3-5 hours), not dose-dependent; 15-minute timing , NPH compatibility , and peakless profile are true.
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Influenza vaccine may be administered annually to:
- A. Patients with an egg allergy
- B. Pregnant patients
- C. Patients age 6 weeks or older
- D. Patients with acute febrile illness
Correct Answer: B
Rationale: Influenza vaccine is safe in pregnancy; egg allergy requires caution, 6 weeks is too young, and fever delays it.
A 24 year-old man with a history of substance abuse is suffering from generalized anxiety disorder. Which of the following drugs would be the most suitable for the management of his condition?
- A. Zolpidem
- B. Buspirone
- C. Midazolam
- D. Triazolam
Correct Answer: B
Rationale: Buspirone, a non-benzodiazepine, treats anxiety without dependence risk.
Tom is taking lithium for bipolar disorder. He should be taught to:
- A. Take his lithium with food
- B. Eat a diet with consistent levels of salt (sodium)
- C. Drink at least 2 quarts of water if he is in a hot environment
- D. Monitor blood glucose levels
Correct Answer: B
Rationale: Consistent sodium intake prevents fluctuations in lithium levels.
Conjunctivitis in a child that is accompanied by acute otitis media is treated with:
- A. Sulfacetamide 10% ophthalmic solution (Bleph-10)
- B. Bacitracin/polymyxin B (Polysporin) ophthalmic drops
- C. Ciprofloxacin (Ciloxan) ophthalmic drops
- D. High-dose oral amoxicillin
Correct Answer: D
Rationale: Conjunctivitis with otitis suggests bacterial cause (e.g., H. influenzae), treated with oral amoxicillin.
What patient populations would the nurse expect is most likely to be prescribed a drug for an off-label use?
- A. Adolescent and middle-aged adult patients
- B. Patients with diabetes or heart disease
Correct Answer: B
Rationale: Patients with chronic conditions like diabetes or heart disease are more likely to receive off-label prescriptions due to limited standard treatment options or the need for alternative therapies when conventional drugs are ineffective. Adolescents and middle-aged adults are less likely unless specific conditions warrant it, but the document cuts off, and based on clinical context, chronic disease patients are a common focus for off-label use.