Questions About Chronic Diseases Related

Review Questions About Chronic Diseases related questions and content

Mr XYZ, a 60-year-old, smoker with DM, hypertension and CKD Stage 3 sees you for routine chronic review. He reports recurrent gout flares past five weeks of increasing intensity and duration which he assumes is due to frequent travel and lack of exercise. His current laboratory results are creatinine 106, eGFR 56, uric acid 400, HbA1c 7.3%, random hypocount 8.5 mmol/L. He is currently taking glipizide 5 mg BD, Metformin 250 mg BD, Amlodipine 5 mg OM. What is the most appropriate management in this patient?

  • A. Offer dietary advice
  • B. Prescribe NSAIDs and medical certificate (MC)
  • C. Increased exercise frequency (e.g. jogging at least 3 times per week)
  • D. Initiate urate lowering therapy using allopurinol with colchicine prophylaxis
Correct Answer: D

Rationale: Gout flares, uric acid 400, CKD 3 allopurinol with colchicine tames crystals, not just diet, NSAIDs, jogging, or smoke quit. Nurses start this chronic uric brake.