Nicotinic receptors are seen in
- A. Skeletal muscle
- B. Visceral smooth muscle
- C. Cardiac muscle
- D. Salivary glands
Correct Answer: A
Rationale: Nicotinic receptors are primarily at skeletal muscle neuromuscular junctions.
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Henry presents to clinic with a significantly swollen, painful great toe and is diagnosed with gout. Of the following, which would be the best treatment for Henry?
- A. High-dose colchicine
- B. Low-dose colchicine
- C. High-dose aspirin
- D. Acetaminophen with codeine
Correct Answer: B
Rationale: Low-dose colchicine effectively treats acute gout with fewer side effects than high-dose ; aspirin worsens gout.
Which of the following is an advantage of sublingual administration?
- A. Rapid absorption
- B. Convenient
- C. Avoid harsh GI environment
- D. Avoid first pass-metabolism
Correct Answer: D
Rationale: Sublingual administration offers rapid absorption , convenience , avoids the GI tract , and bypasses first-pass metabolism ; all are true, but D is a key pharmacological advantage.
Select a drug used in the treatment of primary hyperaldosteronism that may cause hyperkalemia:
- A. Acetazolamide
- B. Mannitol
- C. Torsemide
- D. Spironolactone
Correct Answer: D
Rationale: Spironolactone, an aldosterone antagonist, causes potassium retention.
Which of the following is thyroid hormone:
- A. Triiodthironine
- B. Monoiodthirozine
- C. Diiodthirozine
- D. Octaiodthironine
Correct Answer: A
Rationale: Triiodothyronine (T3) is a key thyroid hormone that regulates metabolism, unlike the others which are not primary hormones.
The client with metastatic breast cancer is receiving tamoxifen. The nurse specifically monitors which laboratory value while the client is taking this medication?
- A. Glucose level
- B. Calcium level
- C. Potassium level
- D. Prothrombin time
Correct Answer: B
Rationale: Tamoxifen may increase calcium, cholesterol, and triglyceride levels. Before the initiation of therapy, a complete blood count, platelet count, and serum calcium levels should be assessed. These blood levels, along with cholesterol and triglyceride levels, should be monitored periodically during therapy. The nurse should assess for hypercalcemia while the client is taking this medication. Signs of hypercalcemia include increased urine volume, excessive thirst, nausea, vomiting, constipation, hypotonicity of muscles, and deep bone and flank pain.