Nokea
Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
- A. Increase blood glucose levels
- B. Produce unexplained diaphoresis
- C. Interfere with the ability of the body to metabolize glucose
- D. Mask the signs and symptoms of altered glucose levels
Correct Answer: D
Rationale: Nonselective beta blockers and alcohol mask hypoglycemia symptoms (e.g., tachycardia), complicating detection.
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Insuline:
- A. Facilitate glucose absorbtion in the small intestines
- B. Increase sensitivity of insuline receptors
- C. Facilitate glucose permeability in the cell and utilization
- D. Increase glycogen storage
Correct Answer: C
Rationale: Insulin facilitates glucose permeability and utilization and increases glycogen synthesis in cells.
The mean weight of 500 college students is 70 kg and the standard deviation is 3 kg. Assuming that the weight is normally distributed, determine how many students weigh 64 kg or less.
- A. 5
- B. 11
- C. 15
- D. 20
Correct Answer: B
Rationale: P(X ≤ 64) equals P(X < 64) in a continuous distribution since P(X=64) = 0. From the previous calculation, P(Z < -2) ≈ 0.0228, so 0.0228 * 500 ≈ 11, consistent with the document.
Up to 21% of Asians are ultra-rapid 2D6 metabolizers, requiring:
- A. A need to monitor drugs metabolized by 2D6 for toxicity
- B. Increased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitors
- C. Decreased conversion of codeine to morphine by CYP 2D6
- D. The need for lowered dosages of drugs, such as beta blockers
Correct Answer: B
Rationale: Ultra-rapid 2D6 metabolizers (e.g., in Asians) need higher SSRI doses due to fast metabolism, unlike toxicity , codeine issues , or lower doses .
Human papillomavirus (HPV) vaccine (Gardasil, Cervarix):
- A. Is a live virus vaccine that provides immunity to six strains of HPV virus
- B. Has a common adverse effect of syncope within 15 minutes of giving the vaccine
- C. Should not be given to males younger than age 12 years
- D. May be given to pregnant women
Correct Answer: B
Rationale: HPV vaccine commonly causes syncope post-injection; it's not live , is approved for males 9+ , and is avoided in pregnancy .
What would be the best source of drug information for a nurse?
- A. Drug Facts and Comparisons
- B. A nurse's drug guide
- C. A drug package insert
- D. The Physicians Drug Reference (PDR)
Correct Answer: B
Rationale: A nurse's drug guide provides nursing implications and patient teaching points that are most useful to nurses in addition to need-to-know drug information in a very user friendly organizational style. Lippincott's Nursing Drug Guide (LNDG) has drug monographs organized alphabetically and includes nursing implications and patient teaching points. Numerous other drug handbooks are also on the market and readily available for nurses to use. Although other drug reference books such as Drug Facts and Comparisons, PDR, and drug package inserts can all provide essential drug information, they will not contain nursing implications and teaching points and can be more difficult to use than nurse's drug guides.