Nokea
What is the advantage of sublingual route of administration of drugs
- A. Prevents first pass effect
- B. Easy to administer
- C. Lipid soluble
- D. Can be spitted out with signs of toxicity
Correct Answer: A
Rationale: Sublingual administration bypasses hepatic first-pass metabolism.
You may also like to solve these questions
Which of the following is a representative of sulfonylurea?
- A. Merformin
- B. Glibenclamide
- C. Acarbose
- D. Liraglutide
Correct Answer: B
Rationale: Glibenclamide is a sulfonylurea that stimulates insulin release from beta cells.
Not an antidepressant
- A. Amitryptilline
- B. Fluoxetin
- C. Trazodone
- D. Pimozide
Correct Answer: D
Rationale: Pimozide is an antipsychotic, not an antidepressant.
A 35-year-old woman has Graves' disease, a small goiter, and symptoms that are deemed 'mild-to-moderate.' Propylthiouracil is prescribed. Which of the following is the most serious adverse response to this drug, for which close monitoring is required?
- A. Agranulocytosis
- B. Cholestatic jaundice
- C. Gout
- D. Renal tubular necrosis
Correct Answer: A
Rationale: Agranulocytosis is a severe, potentially fatal side effect of propylthiouracil requiring close monitoring due to its impact on white blood cell production.
Nonselective beta blockers and alcohol create serious drug interactions with insulin because they:
- A. Increase blood glucose levels
- B. Produce unexplained diaphoresis
- C. Interfere with the ability of the body to metabolize glucose
- D. Mask the signs and symptoms of altered glucose levels
Correct Answer: D
Rationale: Nonselective beta blockers and alcohol mask hypoglycemia symptoms (e.g., tachycardia), complicating detection.
A nurse is preparing to administer a prescribed medication to a client. The nurse integrates knowledge of which of the following as a possible factor that could influence the drug response?
- A. Age
- B. Polypharmacy
- C. Weight
- D. All the above
Correct Answer: D
Rationale: Drug response can be influenced by the following factors: age, polypharmacy, weight, sex, disease, and genetics.