Not metabolized in liver
- A. Cimetidine
- B. Phenytoin
- C. Diazepam
- D. Penicillin G
Correct Answer: D
Rationale: Penicillin G is primarily excreted unchanged by the kidneys, unlike the others metabolized by the liver.
You may also like to solve these questions
Drug of choice in phenothiazine induced parkinsonism is
- A. Levodopa
- B. Haloperidol
- C. Metoclopramide
- D. None of the above
Correct Answer: A
Rationale: Levodopa counters phenothiazine-induced parkinsonism.
If 10 mg of naproxen produces the same analgesic response as 100 mg of ibuprofen, which of the following statements is correct?
- A. Naproxen is more efficacious than is ibuprofen
- B. Naproxen is more potent than ibuprofen
- C. Naproxen is full agonist, and ibuprofen is a partial agonist
- D. Naproxen is a competitive antagonist
Correct Answer: B
Rationale: Lower dose for the same effect indicates naproxen is more potent (lower EC50) than ibuprofen.
A patient who has a long history of alcohol abuse is admitted to the hospital for detoxification. In addition to medications needed to treat withdrawal symptoms, the nurse will anticipate giving intravenous
- A. dopamine to restore blood pressure
- B. fluid boluses to treat dehydration
- C. glucose to prevent hypoglycemia
- D. thiamine to treat nutritional deficiency
Correct Answer: D
Rationale: Thiamine prevents Wernicke's encephalopathy in alcohol detox; glucose follows if needed. Thiamine should be given to prevent Wernicke's encephalopathy in patients treated for alcoholism.
Success rates for smoking cessation using NRT:
- A. Are about the same regardless of the method chosen
- B. Vary from 40% to 50% at 12 months
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: A
Rationale: Success rates are similar across NRT methods (e.g., gum, patch), typically 20-25% at 12 months.
The nurse explains that what drug resource book is compiled from package inserts?
- A. Nurses Drug Guide
- B. Physicians Desk Reference (PDR)
- C. Drug Facts and Comparisons
- D. AMA Drug Evaluations
Correct Answer: B
Rationale: The PDR is a compilation of information found on package inserts. The Nurses Drug Guide uses more easily understood language and incorporates nursing considerations and patient teaching points. Drug Facts and Comparisons includes cost comparison, often not found in other drug resource guides. The AMA Drug Evaluations is far less biased than the PDR and includes drugs still in the research stage of development.