Not metabolized in liver
- A. Cimetidine
- B. Phenytoin
- C. Diazepam
- D. Penicillin G
Correct Answer: D
Rationale: Penicillin G is primarily excreted unchanged by the kidneys, unlike the others metabolized by the liver.
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Cecilia presents with depression associated with complaints of fatigue, sleeping all the time, and lack of motivation. An appropriate initial antidepressant for her would be:
- A. Fluoxetine (Prozac)
- B. Paroxetine (Paxil)
- C. Amitriptyline (Elavil)
- D. Duloxetine (Cymbalta)
Correct Answer: D
Rationale: Duloxetine addresses both depression and fatigue, unlike sedating options.
Which of the following is used for treatment of hyperthyroidism:
- A. Liothironine
- B. Levothiroxine
- C. Propilthiouracil
- D. Liotrix
Correct Answer: C
Rationale: Propylthiouracil inhibits thyroid hormone synthesis, making it a standard treatment for hyperthyroidism.
Success rates for smoking cessation using NRT:
- A. Are about the same regardless of the method chosen
- B. Vary from 40% to 50% at 12 months
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: A
Rationale: Success rates are similar across NRT methods (e.g., gum, patch), typically 20-25% at 12 months.
A 60 year old male patient with a history of postural hypotension has just been diagnosed with benign prostatic hyperplasia. Which ONE of the following drugs is most suitable for the management of his condition?
- A. Prazosin
- B. Terazosin
- C. Doxazosin
- D. Tamsulosin
Correct Answer: D
Rationale: Tamsulosin, a selective alpha-1A blocker, minimizes postural hypotension compared to non-selective options.
Which statement(s) is/are true regarding computerized prescriber order entry (CPOE)?(Select one that does not apply.)
- A. Integrates the ordering system with the pharmacy, laboratory, and nurses
- B. Provides instant access to online information to facilitate patient care needs
- C. Facilitates review of ordered medications for potential drug interactions
- D. Alleviates the need to perform mathematical computations
Correct Answer: D
Rationale: CPOE systems integrate patient information, provide instant access, facilitate review of ordered medications for potential drug interactions, and facilitate review of drugs for appropriateness of dosages. Alleviation of the need to perform mathematical computations is not a component of the CPOE system.
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