Nokea
NSAIDs increase the risk of CNS adverse effects when taken with which group of antibiotics?
- A. Macrolides
- B. Penicillins
- C. Aminoglycosides
- D. Quinolones
Correct Answer: D
Rationale: Quinolones (e.g., ciprofloxacin) with NSAIDs can increase CNS effects like seizures due to GABA inhibition.
You may also like to solve these questions
Zero order kinetics is seen with
- A. Phenytoin
- B. Phenobarbital
- C. Erythromycin
- D. Digoxin
Correct Answer: A
Rationale: Phenytoin exhibits zero-order kinetics at high doses (rate is constant, not proportional).
Irreversible interaction of an antagonist with a receptor is due to:
- A. Ionic bonds
- B. Hydrogen bonds
- C. Covalent bonds
- D. All of the above
Correct Answer: C
Rationale: Irreversible antagonism typically involves covalent bonding, making it permanent.
Digoxin levels need to be monitored closely when the following medication is started:
- A. Loratadine
- B. Diphenhydramine
- C. Ipratropium
- D. Albuterol
Correct Answer: D
Rationale: Albuterol , a beta-agonist, can increase digoxin levels by enhancing its effects, requiring close monitoring; antihistamines and ipratropium have minimal impact.
While receiving treatment for kidney stones, a man complains of swelling and pain in his big toe and is found to have hyperuricemia
- A. Clomiphene
- B. Hydrochlorothiazide
- C. Furosemide
- D. Mifepristone
Correct Answer: B
Rationale: Thiazides like hydrochlorothiazide reduce uric acid excretion, causing hyperuricemia and gout.
Potentially fatal granulocytopenia has been associated with treatment of hyperthyroidism with propylthiouracil. Patients should be taught to report:
- A. Tinnitus and decreased salivation
- B. Fever and sore throat
- C. Hypocalcemia and osteoporosis
- D. Laryngeal edema and difficulty swallowing
Correct Answer: B
Rationale: Fever and sore throat signal granulocytopenia with propylthiouracil; other symptoms are unrelated.