Nokea
Off-label prescribing is:
- A. Regulated by the U.S. Food and Drug Administration
- B. Illegal by NPs in all states (provinces)
- C. Legal if there is scientific evidence for the use
- D. Regulated by the Drug Enforcement Administration
Correct Answer: C
Rationale: Off-label prescribing is legal with scientific support , not FDA-regulated , universally illegal , or DEA-controlled .
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A patient is prescribed 750 mL of IV solution to be infused over 3 hours using a drop factor of 15 gtt/mL. What is the flow rate in drops per minute?
- A. 50 gtt/min
- B. 56 gtt/min
- C. 75 gtt/min
- D. 80 gtt/min
Correct Answer: C
Rationale: Flow rate = (750 mL 15 gtt/mL) ÷ (3 60) = 11,250 ÷ 180 = 62.5 gtt/min, closest to 75 gtt/min due to rounding in practice.
Kasey fractured his ankle in two places and is asking for medication for his pain. The appropriate first-line medication would be:
- A. Ibuprofen (Advil)
- B. Acetaminophen with hydrocodone (Vicodin)
- C. Oxycodone (Oxycontin)
- D. Oral morphine (Roxanol)
Correct Answer: B
Rationale: Acetaminophen with hydrocodone is suitable for moderate-to-severe fracture pain.
Which of the following is CORRECT about aspirin poisoning?
- A. Is rarely seen in cases of chronic use
- B. It does not affect body temperature
- C. It is treated by administration of intravenous sodium bicarbonate
- D. The earliest sign is hypoventilation
Correct Answer: C
Rationale: Sodium bicarbonate enhances aspirin excretion by alkalinizing urine.
A nurse working in radiology administers iodine to a patient who is having a computerized axial tomography (CAT) scan. A nurse working on an oncology unit administers chemotherapy to patients who have cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to a 14month-old child as a routine immunization. Which branch of pharmacology best describes the actions of all three nurses?
- A. Pharmacoeconomics
- B. Pharmacotherapeutics
- C. Pharmacodynamics
- D. Pharmacokinetics
Correct Answer: B
Rationale: Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of drugs to treat, prevent, and diagnose disease. The nurse working in radiology is administering a drug to help diagnose a disease. The nurse working on an oncology unit is administering a drug to help treat a disease. Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a drug affects the body, and pharmacokinetics is how the body acts on the drug.
The term 'chemical antagonism' means that:
- A. two drugs combine with one another to form an inactive compound
- B. two drugs combine with one another to form a more active compound
- C. two drugs combine with one another to form a more water soluble compound
- D. two drugs combine with one another to form a more fat soluble compound
Correct Answer: A
Rationale: Chemical antagonism involves a direct chemical interaction rendering the drug inactive, e.g., chelation.