Nokea
OSHA is a division of the
- A. National Institutes of Health.
- B. Centers for Disease Control and Prevention.
- C. U.S. Department of Labor.
- D. World Health Organization.
Correct Answer: C
Rationale: 1. OSHA stands for Occupational Safety and Health Administration.
2. OSHA is responsible for ensuring safe and healthy working conditions in the US.
3. The U.S. Department of Labor oversees OSHA's operations and regulations.
4. Therefore, the correct answer is C, as OSHA is a division of the U.S. Department of Labor.
5. Other choices are incorrect because they are not directly related to OSHA's jurisdiction or responsibilities.
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In a village, a case of anthrax had been registered. Medical services began epidemiologically indicated specific prophylaxis of population against anthrax. What preparation was used for this purpose?
- A. Anatoxin
- B. Inactivated vaccine
- C. Chemical vaccine
- D. Genetically engineered vaccine
Correct Answer: A
Rationale: The correct answer is A: Anatoxin. An anatoxin is a preparation that contains inactivated toxins produced by the anthrax-causing bacteria. By administering anatoxin, the population can develop immunity against the toxin without being exposed to the live bacteria. This specific prophylaxis approach helps prevent the development of anthrax infection by targeting the toxin itself.
Summary:
- Choice B (Inactivated vaccine) is incorrect because an inactivated vaccine typically contains killed or inactivated whole bacteria, not just the toxins.
- Choice C (Chemical vaccine) is incorrect as there is no such thing as a chemical vaccine; vaccines are biological preparations.
- Choice D (Genetically engineered vaccine) is incorrect because while vaccines can be genetically engineered, the specific term "genetically engineered vaccine" does not accurately describe the prophylaxis used against anthrax in this scenario.
Which of the following is a phase I reaction in biotransformation?
- A. Oxidation
- B. Conjugation
- C. Acetylation
- D. Glucuronidation
Correct Answer: A
Rationale: The correct answer is A: Oxidation. Phase I reactions in biotransformation involve introducing or unmasking functional groups through oxidation, reduction, or hydrolysis. Oxidation reactions typically involve the addition of an oxygen atom or removal of hydrogen atoms, making them common phase I reactions. In this process, enzymes like cytochrome P450 play a crucial role in catalyzing the oxidation reactions.
Conjugation (B), acetylation (C), and glucuronidation (D) are all examples of phase II reactions, which involve the conjugation of the drug or metabolite with endogenous compounds to increase water solubility for excretion. These reactions typically follow phase I reactions and are not classified as phase I reactions in biotransformation.
Which is not true?
- A. Interferon beta is produced by the fibroblasts
- B. Interferon alpha is produced by the leukocytes
- C. Interferon gamma is produced by the lymphocytes
- D. Interferon delta is produced by the macrophages
Correct Answer: D
Rationale: Interferon delta is not a known type of interferon, making choice D incorrect. Interferon beta is indeed produced by fibroblasts (choice A), interferon alpha by leukocytes (choice B), and interferon gamma by lymphocytes (choice C). Each type of interferon is produced by specific cells in the immune system, contributing to the body's defense against viruses and other pathogens.
A child presented with foul-smelling diarrhea. Stool microscopy revealed trophozoites with two nuclei and flagella. What is the causative agent?
- A. Giardia lamblia
- B. Entamoeba histolytica
- C. Trichomonas vaginalis
- D. Balantidium coli
Correct Answer: A
Rationale: The correct answer is A: Giardia lamblia. Giardia lamblia is a protozoan parasite that causes foul-smelling diarrhea. The trophozoites of Giardia lamblia have two nuclei and flagella, which are characteristic features seen on stool microscopy. The presence of these specific features helps differentiate Giardia lamblia from the other options. Entamoeba histolytica (B) typically presents with one nucleus and lacks flagella. Trichomonas vaginalis (C) is a sexually transmitted parasite with a different morphology. Balantidium coli (D) is a ciliated parasite, not flagellated like Giardia lamblia.
A 28 y.o. homeless male was admitted to the hospital because of initial diagnosis "influenza". Roseolo-petechiae rash has appeared on the trunk and internal surfaces of the limbs on the fifth day. Temperature is 410C, euphoria, face and sclera's hyperemia, tongue tremor, tachycardia, splenomegaly, excitement. What is the most probable diagnosis?
- A. Typhus
- B. Alcogolic delirium
- C. Leptospirosis
- D. Abdominal typhoid
Correct Answer: C
Rationale: The most probable diagnosis for the homeless male with symptoms of roseolo-petechiae rash, hyperemia, tachycardia, splenomegaly, and euphoria is Leptospirosis. Leptospirosis is a bacterial infection commonly associated with exposure to contaminated water or soil, which is prevalent in homeless populations. The initial diagnosis of "influenza" fits with the flu-like symptoms. The appearance of roseolo-petechiae rash and other symptoms like hyperemia, tachycardia, splenomegaly, and euphoria are consistent with leptospirosis. The other choices can be ruled out: A) Typhus typically presents with headache, fever, and rash, but not the specific symptoms described. B) Alcoholic delirium is more likely with a history of alcohol abuse and presents with confusion, disorientation, and hallucinations. D) Abdominal typhoid presents with prolonged fever, abdominal pain