Nokea
Penicillin-resistant, beta-lactamase-producing strains must be detected..
- A. After antibiotic therapy is begun
- B. Before antibiotic therapy is begun
- C. During the antibiotic therapy
- D. No importance for the time of detection
Correct Answer: B
Rationale: The correct answer is B: Before antibiotic therapy is begun. Detecting penicillin-resistant, beta-lactamase-producing strains before antibiotic therapy is crucial to ensure proper treatment. If detected after therapy (choice A), it may lead to treatment failure. Detection during therapy (choice C) may result in delayed or ineffective treatment. Choice D is incorrect as early detection is essential for successful management.
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Microscopy of a wound abscess revealed Gram-negative rods producing blue-green pigment with a distinctive odor of jasmine. What is the likely causative agent?
- A. Pseudomonas aeruginosa
- B. Proteus vulgaris
- C. Escherichia coli
- D. Klebsiella pneumoniae
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is known for producing a blue-green pigment called pyocyanin, which gives the characteristic color seen in the wound abscess. The distinctive odor of jasmine is also a key feature of Pseudomonas aeruginosa. Proteus vulgaris (B) and Klebsiella pneumoniae (D) do not produce blue-green pigment or have a jasmine-like odor. Escherichia coli (C) typically does not produce blue-green pigment or have a jasmine-like odor.
Chlorine belongs to which of the following chemical groups?
- A. Halogens
- B. Heavy metals
- C. Phenols
- D. Alcohols
Correct Answer: A
Rationale: The correct answer is A: Halogens. Chlorine belongs to the halogens group because it is a nonmetal element in group 17 of the periodic table. Halogens are highly reactive elements that have 7 electrons in their outer shell, making them eager to gain an electron to achieve stability. Chlorine specifically is a diatomic molecule with the chemical symbol Cl and atomic number 17.
Option B: Heavy metals are elements with high atomic weights and densities, such as lead and mercury, which are not related to chlorine.
Option C: Phenols are a class of organic compounds containing a hydroxyl group bonded to an aromatic ring, not related to chlorine.
Option D: Alcohols are organic compounds characterized by the presence of a hydroxyl group (-OH), also not related to chlorine.
Poxviruses are the largest viruses, almost visible on a light microscope.
- A. TRUE
- B. FALSE
- C. Not Sure
- D. Partially
Correct Answer: A
Rationale: The correct answer is A: TRUE. Poxviruses are indeed the largest viruses, ranging from 200-450 nm in size, which is close to the resolution limit of a light microscope. This makes them almost visible under a light microscope. The other choices are incorrect because poxviruses are not smaller or uncertain in size (choices B and C), nor are they partially visible - they are almost visible due to their relatively large size.
Production of auto-antibodies may be due to:
- A. Emergence of mutant clones of B cells
- B. Production of antibodies against hidden tissues
- C. Genetic factors
- D. All of these
Correct Answer: D
Rationale: Production of auto-antibodies can be due to various factors. Mutant B cell clones can lead to the production of self-reactive antibodies. Antibodies against hidden tissues can also trigger autoimmune responses. Genetic factors play a crucial role in predisposing individuals to autoimmunity. Therefore, the correct answer is D, as all these factors can contribute to the production of auto-antibodies. Choice A is incorrect as it only addresses one possible cause. Choice B is incorrect as it focuses solely on antibodies against hidden tissues. Choice C is incorrect as it overlooks the other potential reasons for auto-antibody production.
The First-line tuberculosis drugs include:
- A. Isoniazid and rifampicin
- B. Penicillin and erythromycin
- C. Trimethoprim and third generation cephalosporins
- D. All the listed above can be used depending on their resistance profile
Correct Answer: A
Rationale: The correct answer is A: Isoniazid and rifampicin. These drugs are considered first-line treatment for tuberculosis due to their high efficacy and low toxicity. Isoniazid targets the cell wall of the tuberculosis bacteria, while rifampicin inhibits RNA synthesis. They are recommended by WHO as the first choice for treating tuberculosis.
Choice B (Penicillin and erythromycin) is incorrect because these antibiotics are not effective against tuberculosis bacteria.
Choice C (Trimethoprim and third generation cephalosporins) is incorrect because they are not considered first-line drugs for tuberculosis treatment.
Choice D (All the listed above can be used depending on their resistance profile) is incorrect because only isoniazid and rifampicin are universally recognized as first-line drugs for tuberculosis regardless of resistance profile.