Prader Willi syndrome:
- A. Is caused by a maternal deletion of a part of chromosome 15
- B. Presents with macrosomia in infancy
- C. Developmental delay is common
- D. Behavioural problems are common
Correct Answer: C
Rationale: Developmental delay is a common feature of Prader Willi syndrome, along with other symptoms such as hypotonia and feeding difficulties in infancy.
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Recognised features in Marfan's syndrome include:
- A. Mutation in fibrillin gene
- B. Mitral valve prolapse
- C. Cognitive impairment
- D. Myopia
Correct Answer: B
Rationale: Mitral valve prolapse
Recognised associations of Addison's disease include:
- A. Neurofibromatosis
- B. Phaeochromocytoma
- C. IDDM
- D. Nephrogenic diabetes insipidus
Correct Answer: C
Rationale: The correct answer is C because IDDM (insulin-dependent diabetes mellitus) is a recognized association of Addison's disease. The other options (a, b, d, e) are less commonly associated.
The nurse is assessing clients in an outpatient diabetic clinic. Which entry provides the best evidence that the client is adhering to the prescribed diabetic regimen?
- A. Hemoglobin A1C of 6.2%
- B. Fasting blood glucose of 130 mg/dL
- C. Positive urine ketones
- D. Self-reported daily blood glucose monitoring
Correct Answer: A
Rationale: A hemoglobin A1C of 6.2% indicates good glycemic control, reflecting adherence to the diabetic regimen.
Anthracycline (doxorubicin) on rare occasion causes acute inflammatory myocardial injury, but more classically results in dilated cardiomyopathy (DCM) in up to 30% of patients with a cumulative dose of doxorubicin exceeding
- A. 250 mg/m²
- B. 350 mg/m²
- C. 450 mg/m²
- D. 550 mg/m²
Correct Answer: D
Rationale: A cumulative dose of doxorubicin exceeding 550 mg/m² is associated with increased risk of dilated cardiomyopathy.
Regarding cranial nerves:
- A. Meningioma of the olfactory groove may cause unilateral anosmia
- B. Lesion in the geniculate ganglion produces hyperacusis
- C. Frontalis muscle is spared in lower motor neuron facial palsy
- D. In oculomotor palsy, pupillary sparing occurs in early stages of external compression of the nerve by a tumour
Correct Answer: A
Rationale: Meningioma affecting the olfactory groove can compress the olfactory nerve, leading to unilateral anosmia.