Nokea
Recurrent Neisserial meningitis in children is suggestive of deficiency of ----- complement.
- A. C3
- B. C4
- C. C8
- D. All
Correct Answer: C
Rationale: Recurrent Neisserial meningitis is suggestive of a deficiency in the terminal complement components, particularly C8, which is crucial for bacterial lysis.
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Vitamin used in the treatment of transient tyrosinemia of newborn?
- A. Vitamin A
- B. Vitamin K
- C. Vitamin E
- D. Vitamin C
Correct Answer: D
Rationale: Vitamin C is used to treat transient tyrosinemia due to its role in tyrosine metabolism.
The radiographic finding of notching of the ribs is associated with
- A. pulmonary hypertension
- B. anomalous pulmonary venous return above the diaphragm
- C. coarctation of the aorta
- D. systemic hypertension
Correct Answer: C
Rationale: Rib notching is a classic radiographic sign of coarctation of the aorta due to collateral vessel development.
The following are causes of congestive heart failure and cardiomegaly during the newborn period but no murmur EXCEPT
- A. endocardial fibroelastosis
- B. asphyxia
- C. glycogen storage disease (Pompe disease)
- D. sepsis
Correct Answer: D
Rationale: Sepsis can cause heart failure and cardiomegaly but often presents with other systemic signs.
Of the following, the cardiac lesion resulting in increased volume load is
- A. valvular pulmonic stenosis
- B. patent ductus arteriosus
- C. valvular aortic stenosis
- D. mitral stenosis
Correct Answer: B
Rationale: Patent ductus arteriosus leads to increased volume load on the left side of the heart.
Maltese crosses' are identified in the urinary sediments in
- A. Niemann Pick disease
- B. Gaucher disease
- C. Krabbe's disease
- D. Fabry disease
Correct Answer: D
Rationale: Fabry disease is characterized by the presence of 'Maltese crosses' in urinary sediments due to glycosphingolipid accumulation.