Recurrent Neisserial meningitis in children is suggestive of deficiency of ----- complement.
- A. C3
- B. C4
- C. C8
- D. All
Correct Answer: C
Rationale: Recurrent Neisserial meningitis is suggestive of a deficiency in the terminal complement components, particularly C8, which is crucial for bacterial lysis.
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Complement system:
- A. Is activated by bacterial endotoxins by the classical pathway
- B. Reduced C3 and C4 are usual findings in acute glomerulonephritis
- C. Hereditary angioneurotic oedema is caused by deficiency of one of the components of the classical pathway of the system
- D. Is part of humoral immunity
Correct Answer: D
Rationale: The complement system is a key component of humoral immunity, playing a role in the immune response to pathogens.
Common causes of recurrent abdominal pain include:
- A. Gilbert syndrome
- B. Chronic constipation
- C. Functional cause
- D. Gastric ulcer
Correct Answer: C
Rationale: Functional abdominal pain is a common cause of recurrent abdominal pain in children, often without an identifiable organic cause.
Complications of long-term TPN administration are:
- A. Selenium deficiency
- B. Abnormal liver function tests
- C. Osteopaenia
- D. Renal failure
Correct Answer: A
Rationale: Selenium deficiency is a known complication of long-term total parenteral nutrition (TPN) due to inadequate trace element supplementation.
Toxoplasma gondii infection in humans causes:
- A. Oral ulcers
- B. Cervical lymphadenopathy
- C. Microcephaly
- D. Chorioretinitis
Correct Answer: D
Rationale: Chorioretinitis is a hallmark of congenital toxoplasmosis, leading to vision impairment.
Prior to the patient being given medication, he becomes hypotensive, mottled, and cold. His heart rate is 240. The next therapeutic step should be
- A. digoxin
- B. synchronized DC cardioversion
- C. lidocaine
- D. defibrillation
Correct Answer: B
Rationale: Synchronized DC cardioversion is indicated for unstable tachycardia unresponsive to pharmacological agents.
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