Nokea
Regarding mitral valve prolapse, all the following are true EXCEPT
- A. it is predominantly in girls
- B. it is usually sporadic
- C. the dominant abnormal signs are auscultatory
- D. antibiotic prophylaxis is recommended during surgery and dental procedures
Correct Answer: D
Rationale: Antibiotic prophylaxis is no longer universally recommended for mitral valve prolapse.
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Recurrent Neisserial meningitis in children is suggestive of deficiency of ----- complement.
- A. C3
- B. C4
- C. C8
- D. All
Correct Answer: C
Rationale: Recurrent Neisserial meningitis is suggestive of a deficiency in the terminal complement components, particularly C8, which is crucial for bacterial lysis.
What is ONE gene mutation typically associated with Marfan’s syndrome?
- A. FBN1
- B. ACTA2
- C. SIX2
- D. TGFBR2
Correct Answer: A
Rationale: The FBN1 mutation is the most commonly identified genetic mutation associated with Marfan's syndrome.
What are FIVE indications for surgical intervention in infective endocarditis?
- A. Heart block
- B. Abscess
- C. Valve dysfunction causing heart failure
- D. Large mobile vegetation
Correct Answer: A
Rationale: These are typical indications for surgery when complications of infective endocarditis progress to life-threatening stages.
Proteins found in muscle fibers include:
- A. Vimentin
- B. Saccharin
- C. Keratin
- D. Desmin
Correct Answer: D
Rationale: Desmin: Desmin is an intermediate filament protein found in muscle cells, providing structural support and maintaining the integrity of muscle fibers.
The differential diagnosis of the patient includes all of the following EXCEPT
- A. rheumatic fever
- B. SLE
- C. chronic atrial fibrillation
- D. postmeningococcal immune complexes
Correct Answer: C
Rationale: Chronic atrial fibrillation is unlikely in an 8-year-old with acute onset symptoms.