Nokea
Reduce the likelihood of therapeutic failure with tamoxifen treatment
- A. Not provided in document
- B. Not provided in document
- C. Not provided in document
- D. Not provided in document
Correct Answer: B
Rationale: This question lacks options, but the answer key (ANS: 2) suggests the second choice. Strategies to reduce therapeutic failure include avoiding CYP2D6 inhibitors to ensure proper metabolism of tamoxifen to its active form.
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You are gathering assessment data from a medication history of a 38-year-old male with four children. What assessment information would be most important in providing care for this patient?
- A. The medication history of the patient's mother and/or father
- B. The name of the patient's pharmacy
- C. Insurance, financial support, and stability for the patient and his family
- D. The last time the patient was hospitalized
Correct Answer: C
Rationale: Insurance and financial stability impact access to medications and adherence, critical for a 38-year-old with family responsibilities.
A patient who has oral candidiasis will begin using nystatin suspension to treat the infection. What information will the nurse include when teaching this patient?
- A. Coat the buccal mucosa with the drug and then rinse your mouth
- B. Gargle with the nystatin and then spit it out without swallowing
- C. Mix the suspension with 4 ounces of water and then drink it
- D. Swish the liquid in your mouth and then swallow after a few minutes
Correct Answer: D
Rationale: Nystatin should coat the mouth and be swallowed for oral candidiasis; spitting or rinsing reduces efficacy. Patients should be taught to swish the suspension in the mouth to coat the tongue and buccal mucosa and then swallow the medication.
The nurse uses what term to describe the drug level required to have a therapeutic effect?
- A. Critical concentration
- B. Dynamic equilibrium
- C. Selective toxicity
- D. Active transport
Correct Answer: A
Rationale: A critical concentration of a drug must be present before a reaction occurs within the cells to bring about the desired therapeutic effect. A dynamic equilibrium is obtained from absorption of a drug from the site of drug entry, distribution to the active site, metabolism in the liver, and excretion from the body to have a critical concentration. Selective toxicity is the ability of a drug to attach only to those systems found in foreign cells. Active transport is the process that uses energy to actively move a molecule across a cell membrane and is often involved in drug excretion in the kidney.
After administering a medication, for what would the nurse assess the patient?
- A. Drug effects
- B. Allergies
- C. Pregnancy
- D. Preexisting conditions
Correct Answer: A
Rationale: After the medication is administered, the nurse assesses the patient for drug affects, both therapeutic and adverse. The nurse would assess the patient for allergies, preexisting conditions, and pregnancy before administering a medication.
Prescribers have been shown to override a medication alert about a patient's allergies when:
- A. The history showed that the patient had tolerated the medication in the past
- B. The benefit outweighed the risk
- C. The medication was therapeutically appropriate and needed
- D. All of the above
Correct Answer: D
Rationale: Prescribers may override alerts if past tolerance, benefit-risk balance, or therapeutic need justifies it.