Regarding cough receptors:
- A. There is increased sensitivity in viral infections
- B. ~2-agonists decrease the sensitivity of cough receptors
- C. Exercise can stimulate the cough receptors in asthmatics
- D. They are predominantly seen in the large airways
Correct Answer: A
Rationale: Cough receptor sensitivity increases during viral infections, leading to heightened cough reflex.
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Regarding idiopathic thrombocytopenic purpura (ITP):
- A. The more severe the disease
- B. the faster is the recovery to therapy
- C. Alloimmunisation occurs due to fetomaternal incompatibility
- D. Splenomegaly is a recognised feature
Correct Answer: C
Rationale: ITP is characterized by low platelet counts due to immune-mediated destruction. Splenomegaly is a recognized feature but the other options are incorrect. Recovery is not necessarily faster with more severe disease alloimmunisation is not a feature of ITP and not all children with platelet counts below 50 000 require hospitalization. IV immunoglobulin is not indicated in all cases.
The pH of urine:
- A. Is a useful indicator of the acid/base balance of blood
- B. Rises on a vegetarian diet
- C. Is determined by the concentration of ammonium
- D. Is lower than 5.5 in renal tubular acidosis
Correct Answer: A
Rationale: Urine pH reflects blood acid/base balance. A vegetarian diet typically raises urine pH, and renal tubular acidosis causes a higher pH, not lower.
In a child with scabies, which of the following is the most appropriate treatment?
- A. Permethrin
- B. Benzoyl peroxide
- C. Hydrocortisone
- D. Calamine lotion
Correct Answer: A
Rationale: Permethrin cream is the most effective treatment for scabies, as it targets the mites causing the infestation.
For one of the following, total repair is really achieved, with no requirement for long-term follow-up
- A. atrial septal defects
- B. ventricular septal defects
- C. pulmonic stenosis
- D. uncomplicated isolated pulmonic stenosis
Correct Answer: D
Rationale: Uncomplicated isolated pulmonic stenosis can often be repaired with no need for long-term follow-up.
The following are transmitted as autosomal dominant traits:
- A. Congenital spherocytosis
- B. Vitamin D-resistant rickets
- C. CAH
- D. Hereditary haemorrhagic telangiectasia
Correct Answer: D
Rationale: Hereditary haemorrhagic telangiectasia is an autosomal dominant disorder. Congenital spherocytosis and Vitamin D-resistant rickets can also be autosomal dominant, but CAH (Congenital Adrenal Hyperplasia) is typically autosomal recessive.
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