Nokea
Regarding idiopathic thrombocytopenic purpura (ITP):
- A. The more severe the disease
- B. the faster is the recovery to therapy
- C. Alloimmunisation occurs due to fetomaternal incompatibility
- D. Splenomegaly is a recognised feature
Correct Answer: C
Rationale: ITP is characterized by low platelet counts due to immune-mediated destruction. Splenomegaly is a recognized feature but the other options are incorrect. Recovery is not necessarily faster with more severe disease alloimmunisation is not a feature of ITP and not all children with platelet counts below 50 000 require hospitalization. IV immunoglobulin is not indicated in all cases.
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List FOUR other cardiac manifestations for Marfan’s syndrome, aside from aortopathy.
- A. Mitral valve prolapse/regurgitation
- B. Calcification of the mitral valve <40 years
- C. Dilation of pulmonary artery
- D. Dilation or dissection of ascending/descending aorta (<50 years old)
Correct Answer: A
Rationale: Marfan's syndrome may involve multiple cardiac complications including mitral valve prolapse and other structural heart abnormalities.
Which is/are true?
- A. Babies are able to respond to sounds in utero
- B. Full term babies at birth are unable to follow a large object with their eyes
- C. A 6-week-old infant would be able to follow a large object through an arc of 135°
- D. Growth velocity of head decreases with age
Correct Answer: A
Rationale: Babies can respond to sounds in utero, and head growth velocity does decrease with age. Full-term babies can follow large objects, and a 6-week-old can follow objects through a smaller arc.
In systemic mastocytosis:
- A. Areas of depigmentation occur
- B. Intermittent flushing is seen
- C. IgE levels are high
- D. Is relieved by aspirin
Correct Answer: B
Rationale: Intermittent flushing is a recognized symptom of systemic mastocytosis due to the release of histamine and other chemicals from mast cells.
Cantwell criteria is used to diagnose
- A. Congenital tuberculosis
- B. Congenital syphilis
- C. Congenital rubella
- D. None of the above
Correct Answer: B
Rationale: The Cantwell criteria are used to diagnose congenital syphilis, based on clinical and laboratory findings.
Corneal opacities are seen in:
- A. Marfan's syndrome
- B. Herpes simplex infection
- C. Hurler syndrome
- D. Osteogenesis imperfecta
Correct Answer: C
Rationale: Corneal opacities are a characteristic feature of Hurler syndrome, a type of mucopolysaccharidosis.