Reye's syndrome, a potentially fatal illness associated with liver failure and encephalopathy is associated with the administration of which over-the-counter (OTC) medication?
- A. acetaminophen (Tylenol)
- B. ibuprofen (Motrin)
- C. aspirin
- D. brompheniramine/pseudoephedrine (Dimetapp)
Correct Answer: C
Rationale: Reye's syndrome is linked to the use of aspirin in children and adolescents, particularly during viral infections. It causes severe liver and brain damage. Acetaminophen, ibuprofen, and antihistamines are not associated with this condition. Avoiding aspirin in pediatric patients is critical to prevent this rare but life-threatening syndrome.
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What is the pharmacological action of meç€æ˜€ormin?
- A. Biguanides
- B. Benzodiazepines
- C. Nitrates
- D. Digitalis glycosides
Correct Answer: A
Rationale: Metformin belongs to the class of medications known as biguanides. Biguanides work primarily by decreasing glucose production in the liver and increasing insulin sensitivity in peripheral tissues, such as muscles. They also help improve glucose uptake and utilization by cells, leading to better control of blood sugar levels. Metformin is commonly used to treat type 2 diabetes mellitus and can also be used in the management of polycystic ovary syndrome (PCOS).
Prototype of narcotic analgesic agents:
- A. morphine
- B. codeine
- C. heroin
- D. meperidine
Correct Answer: A
Rationale: Morphine is the prototype of narcotic analgesic agents. It is a strong opioid analgesic that is commonly used for the relief of severe pain. Morphine acts on the central nervous system to reduce the perception of pain and is often used in medical settings, such as hospitals, to manage post-operative pain or pain associated with certain medical conditions like cancer. Other opioids, such as codeine, heroin, meperidine, and oxycodone, are derived from or related to morphine but may have different or varying levels of potency, side effects, and addiction potential.
A patient in the outpatient oncology clinic complains of fatigue after receiving chemotherapy. Which initial nursing intervention will be most appropriate?
- A. Assess for other factors contributing to her fatigue, such as trouble sleeping.
- B. Encourage a high-protein, high-calorie diet, and design it with the patient.
- C. Refer the patient to a physical therapist to develop a strenuous exercise program.
- D. Encourage the patient to sleep as much as possible during the day to ease fatigue.
Correct Answer: A
Rationale: Fatigue is a common side effect of chemotherapy and can be caused by various factors, including anemia, poor nutrition, sleep disturbances, or psychological stress. The nurse's first step should be to assess for underlying causes of fatigue, such as trouble sleeping, anemia, or depression. Once the cause is identified, appropriate interventions can be implemented, such as dietary changes, sleep hygiene strategies, or treatment for anemia. Encouraging excessive daytime sleep or strenuous exercise without assessment may worsen fatigue or lead to other complications.
Which nursing diagnosis is appropriate for a patient receiving antidysrhythmics?
- A. Risk for infection
- B. Deficient knowledge
- C. Deficient fluid volume
- D. Urinary retention
Correct Answer: C
Rationale: The appropriate nursing diagnosis for a patient receiving antidysrhythmics would be Deficient fluid volume. Antidysrhythmics can have side effects such as electrolyte imbalances, which can lead to fluid volume deficit. Monitoring the patient's fluid intake and output is crucial to prevent dehydration and maintain proper electrolyte balance. Therefore, identifying Deficient fluid volume as a nursing diagnosis allows for appropriate interventions to be implemented to address and prevent this potential complication.
A patient requires a nonopioid medication. The nurse knows that which medication will cause the least gastrointestinal distress?
- A. Aspirin
- B. Ketorolac
- C. Celecoxib
- D. Ibuprofen
Correct Answer: C
Rationale: Celecoxib is a selective COX-2 inhibitor, which means it primarily targets the COX-2 enzyme involved in inflammation and pain while sparing the COX-1 enzyme that protects the stomach lining. This selectivity reduces the risk of gastrointestinal distress, such as ulcers and bleeding, compared to non-selective NSAIDs like aspirin, ketorolac, and ibuprofen. Therefore, celecoxib is the best choice for patients who require a nonopioid medication with minimal gastrointestinal side effects. Nurses should consider this when selecting pain management options for patients with a history of gastrointestinal issues.
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