Scott's seizures are well controlled on topiramate and he wants to start playing baseball. Education for Scott regarding his topiramate includes:
- A. He should not play sports due to the risk of increased seizures
- B. He should monitor his temperature and ability to sweat in the heat while playing
- C. Reminding him that he may need higher dosages of topiramate when exercising
- D. Encouraging him to use sunscreen due to photosensitivity from topiramate
Correct Answer: B
Rationale: Topiramate can impair sweating, increasing heat-related risks during sports.
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What is the correct statement concerning noncompetitive antagonism:
- A. The potency of the drug does not change
- B. the number of receptors able to bind the agonist is affected
- C. by increasing the conc. of the agonist, we cannot overcome the problem
- D. non of the above is wrong
Correct Answer: D
Rationale: All statements are correct: noncompetitive antagonism reduces efficacy (not potency), affects receptor availability, and cannot be overcome by increasing agonist concentration.
Patient education when prescribing colchicine includes:
- A. Colchicine may be constipating
- B. Colchicine always causes some degree of diarrhea
- C. Mild muscle weakness is normal
- D. Moderate amounts of alcohol are safe with colchicine
Correct Answer: B
Rationale: Colchicine commonly causes diarrhea, not constipation ; weakness or alcohol aren't typical advice.
Anticholinesterase inhibitors are used to treat:
- A. Peptic ulcer disease
- B. Myasthenia gravis
- C. Both 1 and 2
- D. Neither 1 nor 2
Correct Answer: B
Rationale: Anticholinesterases (e.g., pyridostigmine) treat myasthenia gravis by increasing acetylcholine.
NSAIDs increase the risk of CNS adverse effects when taken with which group of antibiotics?
- A. Macrolides
- B. Penicillins
- C. Aminoglycosides
- D. Quinolones
Correct Answer: D
Rationale: Quinolones (e.g., ciprofloxacin) with NSAIDs can increase CNS effects like seizures due to GABA inhibition.
The nurse administers a prescribed medication that is supplied as an enteric-coated tablet. The patient asks the nurse about this form of tablet. When describing how this tablet is absorbed, which response by the nurse would be most accurate?
- A. The medication dissolves directly from the stomach into the body.'
- B. The drug breaks up into pieces as it moves through the stomach.'
- C. The medication bypasses the GI tract and goes quickly into the bloodstream.'
- D. The drug dissolves into fragments after it reaches your small intestine.'
Correct Answer: D
Rationale: Enteric-coated tablets disintegrate or fragment after reaching the alkaline medium of the small intestine. Tablets and capsules break up into small particles and dissolve into body fluids in the gastrointestinal tract. Liquids and parenteral drugs are quickly absorbed into the body system.
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