Nokea
Spread of hepatitis C occurs by:
- A. Drug abuse
- B. Seafood consumption
- C. Recombinant factor VIII therapy
- D. Faeco-oral spread
Correct Answer: A
Rationale: Hepatitis C is primarily spread through blood-to-blood contact, such as sharing needles or other equipment to inject drugs.
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Which of the following conditions results primarily from mutation in the gene encoding Vitamin D receptor?
- A. Vitamin D dependent rickets type 1
- B. Vitamin D dependent rickets type 2
- C. X-linked hypophosphatemic rickets
- D. Autosomal dominant hypophosphatemic rickets
Correct Answer: B
Rationale: Vitamin D dependent rickets type 2 is caused by mutations in the vitamin D receptor gene, leading to resistance to vitamin D.
Chief organ systems affected in acute graft-versus-host reaction are:
- A. Skin
- B. Renal system
- C. Gut
- D. CNS
Correct Answer: A
Rationale: The skin is one of the primary organ systems affected in acute graft-versus-host disease. The renal system, gut, and CNS can also be affected, but the skin is the most commonly involved.
Neural crest derivatives include:
- A. Adrenal cortical cells
- B. Melanocytes
- C. Langerhans cells
- D. Gastric epithelial cells
Correct Answer: B
Rationale: Melanocytes are derived from the neural crest and are responsible for pigment production in the skin.
Absent jugular venous pulsations are described in patients with
- A. Atrial paralysis
- B. Budd Chiari syndrome
- C. Endomyocardial fibrosis with giant right atrium
- D. Fontan procedure
Correct Answer: D
Rationale: Absent jugular venous pulsations are described in patients with the Fontan procedure due to the absence of a right atrial pump.
The following antibiotics interfere with bacterial translation:
- A. Penicillin
- B. Ceftriaxone
- C. Azithromycin
- D. Ciprofloxacin
Correct Answer: C
Rationale: Azithromycin, a macrolide antibiotic, inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby interfering with translation.