Taylor is a 10-year-old child diagnosed with major depression. The appropriate first-line antidepressant for children is:
- A. Fluoxetine
- B. Fluvoxamine
- C. Sertraline
- D. Escitalopram
Correct Answer: A
Rationale: Fluoxetine is FDA-approved as a first-line treatment for pediatric depression.
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Aminoglycosides lack activity against streptococci.
- A. TRUE
- B. FALSE
Correct Answer: B
Rationale: Aminoglycosides are effective against some streptococci (e.g., when combined with cell wall-active agents), though they are primarily used for gram-negative bacteria.
An NP would prescribe the liquid form of ibuprofen for a 6-year-old child because:
- A. Drugs given in liquid form are less irritating to the stomach.
- B. A 6-year-old child may have problems swallowing a pill.
- C. Liquid forms of medication eliminate the concern for first-pass effect.
- D. Liquid ibuprofen does not have to be dosed as often as the tablet form.
Correct Answer: B
Rationale: A 6-year-old may struggle to swallow pills, making liquid ibuprofen more practical . Liquid forms don't eliminate first-pass effect or reduce dosing frequency , and irritation isn't a primary concern here.
The health care provider (HCP) prescribes exenatide (Byetta) for a client with type 1 diabetes mellitus who takes insulin. The nurse knows that which of the following is the appropriate intervention?
- A. The medication is administered within 60 minutes before the morning and evening meal.
- B. The medication is withheld and the HCP is called to question the prescription for the client.
- C. The client is monitored for gastrointestinal side effects after administration of the medication.
- D. The insulin is withdrawn from the Penlet into an insulin syringe to prepare for administration.
Correct Answer: B
Rationale: Exenatide (Byetta) is an incretin mimetic used for type 2 diabetes mellitus only. It is not recommended for clients taking insulin. Hence, the nurse should hold the medication and question the HCP regarding this prescription. Although options 1 and 3 are correct statements about the medication, in this situation the medication should not be administered. The medication is packaged in prefilled pens ready for injection without the need for drawing it up into another syringe.
Which of the following is an alfa glucosidase inhibitor:
- A. Rosiglitazone
- B. Stagliptine
- C. Exenatide
- D. Acarbose
Correct Answer: D
Rationale: Acarbose inhibits alpha-glucosidase enzymes in the intestine, delaying carbohydrate digestion and absorption, thus reducing postprandial glucose levels.
A 7-year-old male fell off a wood pile while playing. He has been admitted to the ICU with multiple broken bones and internal bleeding. What should the nurse know about drug therapy in this type of patient?
- A. Adverse effects may be decreased
- B. Therapeutic effects may be increased
- C. Pharmacodynamics may be altered
- D. Pharmacokinetics remain the same
Correct Answer: C
Rationale: Trauma alters pharmacodynamics (drug effects) due to physiological stress and injury responses.
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