The elimination of following drugs is dose dependant except
- A. Phenytoin
- B. Salicylate
- C. Theophylline
- D. Chlorpromazine
Correct Answer: D
Rationale: Chlorpromazine follows first-order kinetics; others exhibit dose-dependent (zero-order) elimination.
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Sarah developed a rash after using a topical medication. This is a type __ allergic drug reaction.
- A. I
- B. II
- C. III
- D. IV
Correct Answer: D
Rationale: A rash from topical medication is a Type IV (delayed hypersensitivity) reaction , typically contact dermatitis, not immediate (I), cytotoxic (II), or immune complex (III).
An NP would prescribe the liquid form of ibuprofen for a 6-year-old child because:
- A. Drugs given in liquid form are less irritating to the stomach.
- B. A 6-year-old child may have problems swallowing a pill.
- C. Liquid forms of medication eliminate the concern for first-pass effect.
- D. Liquid ibuprofen does not have to be dosed as often as the tablet form.
Correct Answer: B
Rationale: A 6-year-old may struggle to swallow pills, making liquid ibuprofen more practical . Liquid forms don't eliminate first-pass effect or reduce dosing frequency , and irritation isn't a primary concern here.
A nurse is teaching a client who has Angina Pectoris and is learning how to treat acute Anginal attacks. The clients asks, What is my next step if I take one tablet, wait 5 minutes, but still have Anginal pain? Which of the following responses should the nurse make?
- A. Take two more sublingual tablets at the same time.
- B. Call the emergency response team.
- C. Take a sustained-release nitroglycerin capsule.
- D. Wait another 5 minutes then take a second sublingual tablet.
Correct Answer: B
Rationale: If pain persists after one dose, call emergency services ; protocol is up to 3 doses 5 minutes apart.
Patient teaching related to amlodipine includes:
- A. Increase calcium intake to prevent osteoporosis from a calcium blockade.
- B. Do not crush the tablet; it must be given in liquid form if the patient has trouble swallowing it.
- C. Avoid grapefruit juice as it affects the metabolism of this drug.
- D. Rise slowly from a supine position to reduce orthostatic hypotension.
Correct Answer: C
Rationale: Grapefruit juice inhibits CYP3A4, increasing amlodipine levels.
Insulin is used for:
- A. Treatment of diabetes mellitus type I only
- B. Treatment of diabetes mellitus type II only
- C. Treatment of diabetes mellitus type III and IV only
- D. Treatment of diabetes mellitus type I and II
Correct Answer: D
Rationale: Insulin is used for both type 1 (insulin-dependent) and type 2 (when other treatments fail) diabetes.
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