Questions and Answers on Respiratory System Related

Review Questions and Answers on Respiratory System related questions and content

The classic pathway of complement activation begins when the protein C1 binds to:

  • A. the cell wall of bacteria.
  • B. the plasma membrane of bacteria.
  • C. two antibodies attached to an antigen.
  • D. a cell surface antigen.
Correct Answer: C

Rationale: The correct answer is C because in the classic pathway of complement activation, C1 binds to two antibodies attached to an antigen, forming an immune complex. This binding triggers a cascade of reactions leading to the activation of complement proteins. Choice A is incorrect as C1 does not bind directly to the cell wall of bacteria. Choice B is incorrect as C1 does not bind to the plasma membrane of bacteria. Choice D is incorrect as C1 does not bind directly to a cell surface antigen. The key step in the classic pathway is the recognition of immune complexes by C1, initiating the complement activation cascade.