LPN Pharmacology Practice Questions

LPN Pharmacology Practice Questions Related

Review LPN Pharmacology Practice Questions related questions and content

The client has been prescribed atorvastatin (Lipitor) for hyperlipidemia. Which instruction should the nurse provide to the client?

  • A. Take the medication in the morning with breakfast.
  • B. Avoid drinking grapefruit juice while taking this medication.
  • C. Increase your intake of dietary fiber while on this medication.
  • D. Avoid eating foods high in potassium.
Correct Answer: B

Rationale: The correct instruction for the nurse to provide to the client prescribed atorvastatin (Lipitor) for hyperlipidemia is to avoid drinking grapefruit juice while taking this medication. Grapefruit juice can interfere with the metabolism of atorvastatin, leading to an increased risk of side effects. It is crucial for the client to adhere to this instruction to ensure the effectiveness and safety of the treatment. Choices A, C, and D are incorrect because taking the medication with breakfast, increasing dietary fiber intake, and avoiding foods high in potassium are not specific instructions related to atorvastatin therapy for hyperlipidemia.

You may also like to solve these questions

Patient education for the elderly should include:

  • A. Explanation of drug purpose
  • B. Instructions for safe administration
  • C. Potential side effects
  • D. All of the above
Correct Answer: D

Rationale: Choice D is correct because explaining purpose (improves adherence), safe administration (prevents errors), and side effects (enhances safety) are all key for elderly education, per geriatric care. Choice A is incorrect alone as it's one aspect. Choice B is wrong by itself because administration is just part. Choice C is incorrect solo since side effects are only one element.

Drugs that use CYP 3A4 isoenzymes for metabolism may:

  • A. Induce the metabolism of another drug
  • B. Inhibit the metabolism of another drug
  • C. Both 1 and 2
  • D. Neither 1 nor 2
Correct Answer: C

Rationale: Choice C is correct because CYP 3A4 drugs can induce (speed up) or inhibit (slow down) metabolism of other drugs sharing this pathway, affecting their levels and efficacy. Choice A is incorrect as it's only half the story—induction happens, but inhibition does too. Choice B is wrong because it misses induction potential. Choice D is incorrect since both effects are well-documented with CYP 3A4.

VKORC1 genetic variations would affect which drug?

  • A. Warfarin
  • B. Codeine
  • C. Acetaminophen
  • D. All of the above
Correct Answer: A

Rationale: Choice A is correct because VKORC1 variants alter warfarin's target enzyme, affecting its anticoagulant effect and requiring dose adjustments. Choice B is incorrect as codeine's action is CYP2D6-mediated, not VKORC1-related. Choice C is wrong because acetaminophen doesn't interact with VKORC1—it's unrelated to coagulation. Choice D is incorrect since only warfarin is impacted by VKORC1 genetics.

Therapeutic drug monitoring would be appropriate for which drug?

  • A. Acetaminophen
  • B. Phenytoin
  • C. Albuterol
  • D. All of the above
Correct Answer: B

Rationale: Choice B is correct because phenytoin has a narrow therapeutic index, requiring monitoring of peak and trough levels to ensure efficacy and avoid toxicity, unlike broader-range drugs. Choice A is incorrect as acetaminophen's wide safety margin and short-term use don't typically need monitoring. Choice C is wrong because albuterol's inhaled route and rapid action don't require blood level checks. Choice D is incorrect since only phenytoin fits the monitoring profile.

Food or drink that should be avoided when taking a prescription for simvastatin includes:

  • A. Milk
  • B. Orange juice
  • C. Grapefruit juice
  • D. Green leafy vegetables
Correct Answer: C

Rationale: Choice C is correct because grapefruit juice inhibits CYP3A4, which metabolizes simvastatin, increasing drug levels and rhabdomyolysis risk, so it's to be avoided. Choice A is incorrect as milk doesn't affect simvastatin significantly. Choice B is wrong because orange juice has no notable interaction. Choice D is incorrect since green leafy vegetables don't impact simvastatin metabolism.

Copyright © 2025 Nokea. All rights reserved.