Nokea
The drug of choice in the management of eclampsia is
- A. Phenobarbitone
- B. Magnesium sulphate
- C. Calcium gluconate
- D. Sodium bicarbonate
Correct Answer: B
Rationale: The correct answer is B: Magnesium sulphate. It is the drug of choice for managing eclampsia due to its ability to prevent and control seizures. Magnesium sulfate acts as a central nervous system depressant and smooth muscle relaxant, helping to prevent further seizures. Phenobarbitone (A) is not the first-line treatment for eclampsia. Calcium gluconate (C) is used to counteract calcium channel blocker toxicity, not for eclampsia. Sodium bicarbonate (D) is used to treat metabolic acidosis, not eclampsia.
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How does the maternal microbiome influence the health of the fetus during pregnancy?
- A. By increasing fetal weight
- B. By altering immune development
- C. By reducing placental oxygen levels
- D. By enhancing amniotic fluid
Correct Answer: B
Rationale: The correct answer is B: By altering immune development. The maternal microbiome plays a crucial role in shaping the fetal immune system during pregnancy. Microbes in the mother's body can influence the development of the fetus's immune system through various mechanisms, such as immune cells crossing the placenta. This interaction helps the fetus develop tolerance to maternal antigens.
Choice A (By increasing fetal weight) is incorrect because the maternal microbiome's influence is not primarily related to weight gain. Choice C (By reducing placental oxygen levels) is incorrect as it does not directly relate to the immune system development. Choice D (By enhancing amniotic fluid) is incorrect as the main influence is on the immune system rather than amniotic fluid enhancement.
In myelodysplastic syndromes, the primary indications for splenectomy include
- A. Major hemolysis unresponsive to medical management
- B. Severe symptoms of massive splenomegaly
- C. Sustained leukocyte elevation above 30,000 cells/µL
- D. Portal hypertension
Correct Answer: C
Rationale: The correct answer is C. In myelodysplastic syndromes, splenectomy is indicated for sustained leukocyte elevation above 30,000 cells/µL to manage symptomatic splenomegaly and cytopenias. This is because an enlarged spleen can sequester and destroy blood cells, leading to low blood cell counts. Choices A, B, and D are incorrect as splenectomy is not typically indicated for major hemolysis unresponsive to medical management, severe symptoms of massive splenomegaly, or portal hypertension in the context of myelodysplastic syndromes.
The fetal head retracting against the perineum is a
- A. Gaskin sign
- B. Turtle sign
- C. Klumpke sign
- D. Chignon sign
Correct Answer: B
Rationale: The correct answer is B: Turtle sign. This occurs when the fetal head retracts against the perineum during delivery, resembling a turtle retracting into its shell. This indicates fetal shoulder dystocia, a serious complication. Gaskin sign (A) refers to the position of the mother during labor. Klumpke sign (C) is related to brachial plexus injuries during delivery. Chignon sign (D) is not a recognized term in obstetrics.
Outline four (4) causes of obstructed labour:
- A. Fetal macrosomia
- B. Malpresentation
- C. Pelvic abnormalities
- D. All of the above
Correct Answer: D
Rationale: The correct answer is D, "All of the above." Fetal macrosomia, malpresentation, and pelvic abnormalities are all known causes of obstructed labor. Fetal macrosomia refers to a large baby, which can lead to difficulty in passing through the birth canal. Malpresentation occurs when the baby is not positioned optimally for delivery, such as breech or transverse positions. Pelvic abnormalities, such as a contracted pelvis, can impede the baby's passage during labor. Therefore, selecting option D is appropriate as it encompasses all the major causes of obstructed labor. Choices A, B, and C are not individually comprehensive enough to cover all potential causes of obstructed labor.
TB in pregnancy predisposes a mother to premature labour due to
- A. Poor maternal appetite
- B. Severe anaemia experienced
- C. Adverse reactions of anti-TB drugs
- D. The fever experienced
Correct Answer: D
Rationale: The correct answer is D. TB in pregnancy can lead to premature labor due to the fever experienced. Fever increases the risk of premature labor by triggering uterine contractions. Poor maternal appetite (A) and severe anemia (B) may impact the mother's health but are not directly linked to premature labor. Adverse reactions of anti-TB drugs (C) could potentially affect the mother's health but are not a direct cause of premature labor.