The elderly are at high risk of ADRs due to:
- A. Having greater muscle mass than younger adults, leading to higher volume of distribution
- B. The extensive studies that have been conducted on drug safety in this age group
- C. The blood-brain barrier being less permeable, requiring higher doses to achieve therapeutic effect
- D. Age-related decrease in renal function
Correct Answer: D
Rationale: Age-related renal decline slows drug clearance, raising ADR risk in the elderly, unlike muscle mass , studies , or BBB .
You may also like to solve these questions
Which priority action should be implemented when hives are assessed on a patient started on a new medication?
- A. Notify physician of allergic reaction
- B. Notify physician of idiosyncratic reaction
- C. Notify physician of potential teratogenicity
- D. Notify physician of potential tolerance
Correct Answer: A
Rationale: Hives indicate an allergic reaction (hypersensitivity), requiring immediate physician notification for management.
A home care nurse visits a client recently diagnosed with diabetes mellitus who is taking Humulin NPH insulin daily. The client asks the nurse how to store the unopened vials of insulin. The nurse tells the client to:
- A. Freeze the insulin.
- B. Refrigerate the insulin.
- C. Store the insulin in a dark, dry place.
- D. Keep the insulin at room temperature.
Correct Answer: B
Rationale: Insulin in unopened vials should be stored under refrigeration until needed. Vials should not be frozen. When stored unopened under refrigeration, insulin can be used up to the expiration date on the vial. Options 1, 3, and 4 are incorrect.
Which of the following are poorly perfused tissues?
- A. Heart
- B. Brain
- C. Liver
- D. Kidneys
Correct Answer: B
Rationale: This appears to be a trick question; heart, brain, liver, and kidneys are well-perfused. Assuming intent was poorly perfused, none fit, but B (Brain) is least correct here as it's well-perfused.
The nurse applies the nursing process in medication therapy to ensure what?
- A. That medications are given at the right time
- B. That care is efficient and effective
- C. That the right dose of the drug is given to the patient
- D. That the right drug is given to the right patient at the right time
Correct Answer: B
Rationale: The nursing process ensures efficient, effective care, encompassing all aspects of safe administration.
Chlorpromazine can block following receptors EXCEPT:
- A. Dopamine
- B. Beta adrenergic
- C. Alpha adrenergic
- D. Muscarinic
Correct Answer: B
Rationale: Chlorpromazine, a typical antipsychotic, blocks dopamine, alpha-adrenergic, and muscarinic receptors but has minimal effect on beta-adrenergic receptors, which are not its primary target.