Which of the following antiarrhythmic agents has the longest plasma half-life?
- A. Amiodarone
- B. Disopyramide
- C. Quinidine
- D. Disopyramide
Correct Answer: A
Rationale: Amiodarone has a half-life of weeks due to extensive tissue distribution.
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Which of the following medications is classified as a Class IA antiarrhythmic?
- A. Amiodarone
- B. Quinidine
- C. Sotalol
- D. Diltiazem
Correct Answer: B
Rationale: Quinidine is a Class IA antiarrhythmic, blocking sodium channels and prolonging the action potential.
A nurse is caring for a client who has a new prescription for Valproic Acid. The nurse should instruct the client that while taking this medication he will need to have which of the following laboratory tests completed periodically?
- A. Thrombocyte count
- B. Hematocrit
- C. Amylase
- D. Kidney function tests
Correct Answer: A
Rationale: Valproic acid requires monitoring of platelets for bleeding risk and liver function for hepatotoxicity.
A nurse is administering a Dopamine infusion at a low dose to a client who has severe heart failure. Which of the following findings is an expected effect of this medication?
- A. Lowered heart rate
- B. Increased myocardial contractility
- C. Decreased conduction through the AV node
- D. Vasoconstriction of renal blood vessel
Correct Answer: B
Rationale: Low-dose dopamine increases contractility via beta-adrenergic effects, improving cardiac output.
A man is given a drug to reduce thyroid gland size and vascularity before surgical thyroidectomy. Which mechanism is responsible for its use in this setting?
- A. inhibition of the sodium/iodide symporter
- B. inhibition of thyroperoxidase
- C. inhibition of TSH secretion
- D. inhibition of thyroid hormone release
Correct Answer: D
Rationale: Inhibition of thyroid hormone release (e.g., by iodides) reduces gland size and vascularity pre-surgery.
A nurse is preparing to administer an intramuscular injection to a patient for the first time. Which of the following would be most important for the nurse to do?
- A. Obtain the patient's allergy history.
- B. Obtain information about the drug.
- C. Inquire if the patient has any objections to syringes.
- D. Discuss the dosage with other nurses.
Correct Answer: A
Rationale: Before giving any drug for the first time, the nurse should ask the patient about any known allergies as well as any family history of allergies. The nurse need not particularly obtain information about the drug as it has been prescribed by the physician, but needs to be aware of the adverse effects it may cause. There is also no need to discuss the dosage with other nurses or to find out if the client has any objections to syringes. However, the nurse should help allay the patient's fears by reassuring him or her about the administration.
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