Nokea
The patient is taking a 2-mg dose of ropinerol XR. The drug has a half-life of 12 hours. How long will it be before only 0.25 mg of this drug remains in the patient's system?
- A. 24 hours
- B. 36 hours
- C. 48 hours
- D. 60 hours
Correct Answer: B
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to half of the peak level it previously achieved. At 12 hours there will be 1 mg of the drug available to the body. At 24 hours there will be 0.5 mg, at 36 hours there will be 0.25 mg, at 48 hours there will be 0.125 mg, and at 60 hours there will be 0.0625 mg.
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Patients whose total dose of prednisone will exceed 1 gram will most likely need a second prescription for:
- A. Metformin, a biguanide to prevent diabetes
- B. Omeprazole, a proton pump inhibitor to prevent peptic ulcer disease
- C. Naproxen, an NSAID to treat joint pain
- D. Furosemide, a diuretic to treat fluid retention
Correct Answer: B
Rationale: High-dose prednisone risks ulcers, warranting omeprazole; diabetes or fluid are less immediate.
A nurse is caring for a 77-year-old patient. The nurse would know that a normal physiologic change that must be considered when planning drug therapy, and is associated with aging is what?
- A. Blood volume decreases
- B. Subcutaneous tissue increases
- C. Total body water increases
- D. Muscle mass increases
Correct Answer: A
Rationale: Aging reduces blood volume, altering drug distribution and requiring dosage adjustments.
Which of the following names may be assigned to a drug during the process of development? (Select one that does not apply.)
- A. Chemical name
- B. Official name
- C. Pharmacologic name
- D. Trade name
Correct Answer: C
Rationale: Throughout the process of development, drugs may have several names assigned to them including a chemical name, a generic (nonproprietary) name, an official name, and a trade or brand name.
A nurse is teaching a client who has Graves' disease about her prescribed medications. Which of the following statements by the client indicates an understanding of the use of Propranolol in the treatment of Graves' disease?
- A. Propranolol helps increase blood flow to my thyroid gland.
- B. Propranolol is used to prevent excess glucose in my blood.
- C. Propranolol will decrease my tremors and fast heart beat.
- D. Propranolol promotes a decrease of thyroid hormone in my body
Correct Answer: C
Rationale: Propranolol reduces tremors and tachycardia in Graves' disease by blocking beta-adrenergic effects.
What is the role of calcium supplements when patients take bisphosphonates?
- A. They must be restricted to allow the medication to work
- B. They must be taken in sufficient amounts to provide foundational elements for bone growth
- C. They must be taken at the same time as the bisphosphonates
- D. They only work with bisphosphonates if daily intake is restricted
Correct Answer: B
Rationale: Calcium supports bone health with bisphosphonates but must be timed separately (not C) to avoid interference.