NCLEX PN Exam Cram Related

Review NCLEX PN Exam Cram related questions and content

The factor that most determines drug distribution is:

  • A. vascular perfusion of the tissue or organ.
  • B. salt form.
  • C. drug interactions.
  • D. steady state.
Correct Answer: A

Rationale: The correct answer is 'vascular perfusion of the tissue or organ.' Drug distribution is primarily determined by how well the circulatory system delivers the drug to various tissues and organs. Adequate perfusion ensures proper distribution of the drug throughout the body. While the salt form (choice B), drug interactions (choice C), and steady state (choice D) can influence drug efficacy and metabolism, they are not as crucial as vascular perfusion for the initial distribution of a drug.