Nokea
The first laboratory value indication that vitamin B12 therapy is adequately treating pernicious anemia is:
- A. Hematocrit levels start to rise
- B. Hemoglobin levels return to normal
- C. Reticulocyte count begins to rise
- D. Vitamin B12 levels return to normal
Correct Answer: C
Rationale: Reticulocyte count rise signals early bone marrow response to B12, preceding hemoglobin or hematocrit increases.
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A nurse is preparing to administer acetaminophen 650 mg PO every 6 hr PRN for pain. The amount available is acetaminophen liquid 500 mg/5 mL. how many mL should the nurse administer per dose? (Round the answer to the nearest tenth. Use a leading zero if it applies. Do not use a trailing zero.)
- A. 6.5
- B. 5
- C. 4.8
- D. 6
Correct Answer: A
Rationale: Calculation: 650 mg ÷ (500 mg/5 mL) = 6.5 mL, matching the answer.
The patient is a 6-year-old child who is taking 125 mg of amoxicillin every 6 hours. Assuming that the half-life of Amoxicillin is 3 hours, how much Amoxicillin would be in the child's body at the time of the next administration of the drug?
- A. 62.5 mg
- B. 46.875 mg
- C. 31.25 mg
- D. 15.625 mg
Correct Answer: C
Rationale: The half-life of a drug is the time it takes for the amount of drug in the body to decrease to 1 half the peak level it previously achieved. Option A would occur at 3 hours after the original dose of amoxicillin. Option B would occur 4½ hours after the original dose. Option C would occur at 6 hours after the original dose. Option D would occur at 7½ hours after the original dose.
Which of the following is antithyroidal drugs:
- A. Thyroxine
- B. Liothironine
- C. Propilthyouracil
- D. Triiodthironine
Correct Answer: C
Rationale: Propilthyouracil (propylthiouracil) is an antithyroid drug that inhibits thyroid hormone synthesis by blocking the iodination of tyrosine residues in thyroglobulin.
A patient is brought to the emergency department by a family member. The patient reports seeing colored lights and describes feeling bugs crawling under the skin. The nurse suspects that this patient is abusing which drug?
- A. Alcohol
- B. Cocaine
- C. LSD
- D. Methamphetamine
Correct Answer: B
Rationale: Cocaine causes stimulant psychosis with visual (lights) and tactile (bugs) hallucinations; LSD differs in effect. A stimulant psychosis can occur with chronic use of any stimulant and, with cocaine, progresses to visual hallucinations of colored lights and tactile hallucinations of bugs crawling under the skin.
Prostaglandins play pathophysiological role in the following EXCEPT:
- A. Patency of ductus arteriosus
- B. Regulation of renal tubular salt absorption
- C. Ventricular remodelling after myocardial infarction
- D. Initiation of labour
Correct Answer: C
Rationale: Prostaglandins maintain ductus arteriosus patency, regulate renal salt absorption, and initiate labor, but ventricular remodeling post-myocardial infarction is primarily driven by other factors like cytokines and neurohormones.