Nokea
The following conditions can present in a newborn infant as a bullous eruption:
- A. Syphilis
- B. Mast cell disease
- C. Epidermolysis bullosa
- D. Phenylketonuria
Correct Answer: C
Rationale: Epidermolysis bullosa is a genetic condition causing blistering of the skin. Syphilis and mast cell disease can also cause bullous eruptions, but phenylketonuria does not.
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Which of the following statements is true regarding alcohol septal ablation?
- A. Indicated when dynamic LV outflow gradient is more than 50 mm Hg at rest
- B. Targeted septal thickness less than 16 mm is a contraindication
- C. Usually preferred over surgical myomectomy
- D. Reduces risk of sudden death
Correct Answer: A
Rationale: Alcohol septal ablation is indicated when the dynamic LV outflow gradient is more than 50 mm Hg at rest.
Common reasons for doing a BMT in children are:
- A. SCID (severe combined immunodeficiency)
- B. Acute lymphoblastic leukemia
- C. CML
- D. Gaucher's disease
Correct Answer: A
Rationale: The correct answer is A because SCID is a primary indication for bone marrow transplant (BMT) in children. The other options (b-e) are also indications but less common.
The following are true statements:
- A. Tissue plasminogen activator is derived from endothelium
- B. Heparin acts through antithrombin III
- C. Protein C deficiency is autosomal recessive transmitted
- D. Protein C is vitamin K dependent
Correct Answer: B
Rationale: Heparin acts through antithrombin III: Heparin enhances the activity of antithrombin III, which inhibits thrombin and other clotting factors, helping prevent clot formation.
What are THREE long-term complications in repaired Tetralogy of Fallot?
- A. Arrhythmia
- B. Pulmonary valve insufficiency
- C. Sudden Death
- D. Recurrent PS
Correct Answer: D
Rationale: Patients with repaired Tetralogy of Fallot are at risk of long-term complications such as recurrent pulmonary stenosis, arrhythmias, and valve insufficiencies.
Hypothalamic nuclei are responsible for:
- A. Control of hunger
- B. Temperature control
- C. Maintaining osmolarity of extracellular fluid
- D. Secretion of thyrotrophin
Correct Answer: A
Rationale: The hypothalamus plays a key role in regulating hunger through various nuclei and hormonal signals.