The following relationship exist adrenal steroidal hormones, corticotropin and hypothalamic hormones.
- A. Short direct connection
- B. Long direct connection
- C. Short negative feedback
- D. Long negative feedback
Correct Answer: D
Rationale: Adrenal steroids, corticotropin (ACTH), and hypothalamic CRH form a long negative feedback loop in the HPA axis.
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Chlorpromazine can block following receptors EXCEPT:
- A. Dopamine
- B. Beta adrenergic
- C. Alpha adrenergic
- D. Muscarinic
Correct Answer: B
Rationale: Chlorpromazine, a typical antipsychotic, blocks dopamine, alpha-adrenergic, and muscarinic receptors but has minimal effect on beta-adrenergic receptors, which are not its primary target.
While caring for a patient with a history of hypothyroidism, the nurse expects which of the following medications to be included in the patient's medication list?
- A. Levothyroxine sodium (Synthroid)
- B. Estrogen (Estradiol)
- C. Iodine 131
- D. Carbimazole (Methimazole)
Correct Answer: A
Rationale: Levothyroxine (Synthroid) is the standard treatment for hypothyroidism, replacing thyroid hormone; carbimazole treats hyperthyroidism, and iodine 131 is for ablation.
A nurse is preparing to administer Amoxicillin 20 mg/kg/day PO to divide equally every 12 hr to a preschooler who weighs 44 lb. The amount available is amoxicillin suspension 250 mg/5 mL. how many mL should the nurse administer per dose? (Round the answer to the nearest whole number. Do not use a trailing zero.)
- A. 4
- B. 7
- C. 1
- D. 10
Correct Answer: A
Rationale: Calculation: 44 lb = 20 kg; 20 mg/kg/day 20 kg = 400 mg/day; 400 mg ÷ 2 doses = 200 mg/dose; 200 mg ÷ (250 mg/5 mL) = 4 mL, matching the answer.
A nurse is caring for a 77-year-old patient. The nurse would know that a normal physiologic change that must be considered when planning drug therapy, and is associated with aging is what?
- A. Blood volume decreases
- B. Subcutaneous tissue increases
- C. Total body water increases
- D. Muscle mass increases
Correct Answer: A
Rationale: Aging reduces blood volume, altering drug distribution and requiring dosage adjustments.
Which of the following statements about NSAIDs is false?
- A. NSAIDs are not recommended during pregnancy
- B. NSAIDs increase renal blood flow
- C. NSAIDs reduce the therapeutic effect of SSRIs
- D. NSAIDs have a hypocoagulability effect
Correct Answer: B
Rationale: NSAIDs decrease renal blood flow by inhibiting prostaglandins, making this statement false.