The following statements are true regarding a screening test:
- A. Sensitivity indicates the proportion of true positives
- B. Specificity indicates the proportion of true negatives
- C. Sensitivity is inversely related to specificity
- D. Prevalence affects predictive value
Correct Answer: D
Rationale: Prevalence affects predictive value
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Uncommon complications of severe falciparum malaria are:
- A. Stroke
- B. Anaemia
- C. Hepatitis
- D. Jaundice
Correct Answer: A
Rationale: The correct answer is A because stroke is an uncommon complication of severe falciparum malaria. The other options (b-e) are more common complications.
SVT in children differ from physiologic sinus tachycardia by all the following EXCEPT
- A. sudden onset and termination
- B. persistent ventricular rate of >180 bpm
- C. fixed RR interval on ECG
- D. evident change in heart rate with activity
Correct Answer: D
Rationale: Physiologic sinus tachycardia can show changes in heart rate with activity, unlike SVT which has a fixed rate.
The following enzymes and inhibitors are matched correctly:
- A. Xanthine oxidase-allopurinol
- B. Enolase-fluoride
- C. Cholinesterase-physostigmine
- D. Ceruloplasmin-penicillamine
Correct Answer: A
Rationale: Xanthine oxidase-allopurinol: Allopurinol inhibits xanthine oxidase, which plays a role in purine metabolism, and is used to treat gout and prevent uric acid buildup.
All the following statements about spontaneous coronary artery dissection are true, except
- A. More common in young females
- B. Proximal coronary involvement associated with immuno-inflammatory disease
- C. Intra-coronary imaging shows 'accordion sign'
- D. Physical stress precipitates it by causing intimal tear
Correct Answer: C
Rationale: The 'accordion sign' is not typically associated with spontaneous coronary artery dissection.
Which is the most common causative agent of bacterial endocarditis?
- A. Staphylococcus albus
- B. Streptococcus hemolyticus
- C. Staphylococcus albicans
- D. Streptococcus viridans
Correct Answer: D
Rationale: S. viridans is the most common causative agent in bacterial (infective) endocarditis.
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