Nokea
The following statements regarding retinoblastoma are correct:
- A. It is usually fatal even if diagnosis is made early
- B. The tumour is heritable
- C. They may occur bilaterally
- D. The finding of leucorrhoea suggests the diagnosis
Correct Answer: B
Rationale: Retinoblastoma is heritable and can occur bilaterally. Early diagnosis improves prognosis, and leucorrhoea is not associated with retinoblastoma.
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A pulmonary embolus occurring while the patient is on the combined oral contraceptive pill:
- A. Is more likely in anti-thrombin III deficiency
- B. Is more likely in protein C deficiency
- C. Is an absolute contraindication to the combined pill
- D. Is an increased risk in smokers
Correct Answer: A
Rationale: Anti-thrombin III deficiency increases the risk of thromboembolic events, including pulmonary embolism, especially in patients on the combined oral contraceptive pill.
ECG
- A. Bifid P waves in large VSD
- B. Complete Ht block in cyanotic attacks of fallots
- C. RBBB in Ebstein anomaly
- D. Right axis deviation in tricuspid atresia
Correct Answer: C
Rationale: In Ebstein's anomaly, right bundle branch block (RBBB) is commonly seen on ECG.
Skin lesions characteristically associated with CNS problems:
- A. Dermatitis herpetiformis
- B. Vitiligo
- C. Strawberry angioma on face
- D. Axillary freckling
Correct Answer: D
Rationale: Axillary freckling
In Wolff-Parkinson-White syndrome:
- A. The abnormal pathway is between the atrial and ventricular myocardium
- B. Wide QRS complexes occur more frequently than narrow QRS
- C. Narrow QRS complexes are regular
- D. Verapamil is the treatment of choice for atrial fibrillation
Correct Answer: B
Rationale: In Wolff-Parkinson-White syndrome, a wide QRS complex is often seen due to the presence of an accessory pathway that bypasses the normal conduction system.
Cytosolic glycogen accumulation does not occur in
- A. Pompe disease
- B. Mc Ardle's disease
- C. Phosphofructokinase deficiency
- D. Phosphoglycerate kinase deficiency
Correct Answer: D
Rationale: Phosphoglycerate kinase deficiency does not lead to cytosolic glycogen accumulation.