ATI Immune System Quizlet Related

Review ATI Immune System Quizlet related questions and content

The interaction of a TCR with its specific antigen is denoted as "signal 1" of activation and does NOT need the contribution of which of the following components

  • A. TCR α-chain
  • B. TCR β-chain
  • C. 28
  • D. MHC molecule
Correct Answer: C

Rationale: Step-by-step rationale:
1. "Signal 1" activation requires TCR to interact with its specific antigen.
2. TCR consists of α and β chains, which are essential for antigen recognition.
3. MHC molecule is crucial for presenting antigens to TCR for recognition.
4. Choice C (28) is not a component involved in TCR-antigen interaction.
5. Therefore, the correct answer is C as it does not contribute to "signal 1" activation.

Summary:
A and B are incorrect as TCR α and β chains are necessary for antigen recognition.
D is incorrect as MHC molecule is essential for presenting antigens to TCR.
C is correct as it is not involved in the TCR-antigen interaction process.