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The most common causative agent of nosocomial infections are:
- A. E.Coli, S. aureus, L. monocytogenes
- B. E. Coli, S. aureus, Enterobacteriacae
- C. S. epidermidis, E.Coli, Enterococcus spp.
- D. None of the above
Correct Answer: C
Rationale: Rationale: Choice C is correct because Staphylococcus epidermidis, Escherichia coli, and Enterococcus spp. are common causative agents of nosocomial infections due to their presence on the skin, in the gut, and in healthcare settings. S. aureus and L. monocytogenes (Choice A) are also important pathogens but are less common in nosocomial infections. Enterobacteriaceae (Choice B) are a large family of bacteria that can cause infections but are not as commonly associated with nosocomial infections compared to the organisms in Choice C. The correct answer (Choice C) encompasses pathogens commonly found in healthcare settings, making it the most suitable option.
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A 23 year old female patient complains about periodical chill and body temperature rise up to 40oC, sense of heat taking turns with profuse sweating. The patient has had already 3 attacks that came once in two days and lasted 12 hours. She has lived in Africa for the last 2 months. Liver and spleen are enlarged. In blood: erythrocytes - 2,5x1012/l. What is the most probable diagnosis?
- A. Malaria
- B. Spotted fever
- C. Sepsis
- D. Haemolytic anaemia
Correct Answer: A
Rationale: The most probable diagnosis is A: Malaria. The patient's symptoms of periodic chills, high fever, and profuse sweating, along with living in Africa where malaria is endemic, strongly suggest malaria. The enlarged liver and spleen are consistent with malaria infection. The low erythrocyte count indicates hemolysis, a common feature of malaria. Spotted fever and sepsis do not typically present with the same pattern of symptoms and travel history as seen in this case. Haemolytic anaemia would not explain the patient's fever episodes and other symptoms. Therefore, based on the symptoms, travel history, and laboratory findings, malaria is the most likely diagnosis.
Chemically an antigen may be:
- A. Lipid
- B. Protein
- C. Polysaccharide
- D. Any of these
Correct Answer: D
Rationale: The correct answer is D because antigens can be composed of lipids, proteins, or polysaccharides. Antigens are molecules that can elicit an immune response in the body. They can be diverse in their chemical composition, leading to the recognition and response by the immune system. Therefore, the correct choice is D as antigens can be any of these chemical components. Choices A, B, and C are incorrect because they each represent a possible chemical composition of antigens, but the flexibility of antigens to be made up of any of these components makes D the most accurate choice.
An outbreak of food poisoning was recorded in an urban settlement. The illness was diagnosed as botulism on the grounds of clinical presentations. What foodstuffs should be chosen for analysis in the first place in order to confirm the diagnosis?
- A. Tinned food
- B. Potatoes
- C. Pasteurized milk
- D. Boiled meat
Correct Answer: A
Rationale: The correct answer is A: Tinned food. Botulism is often caused by the botulinum toxin produced by the bacterium Clostridium botulinum, which can be present in improperly canned foods. Analyzing tinned food allows for direct detection of the toxin or bacteria, confirming the diagnosis. Potatoes, pasteurized milk, and boiled meat are less likely sources of botulism compared to tinned food, making them less suitable for initial analysis in this case.
A pregnant woman complains of vaginal mucosa irritation, itching and genital tracts secretion. Bacterioscopy of vaginal smears revealed large gram-positive oval oblong cells that form pseudomicelium. What is the most probable channel of infection?
- A. Endogenous infection
- B. Sexual transmission
- C. Contact infection
- D. Vector-borne transmission
Correct Answer: B
Rationale: The correct answer is B: Sexual transmission. The symptoms described are indicative of a vaginal yeast infection caused by Candida albicans. The presence of large gram-positive oval oblong cells forming pseudomycelium is characteristic of Candida infection. Sexual transmission is the most probable channel of infection as Candida can be transmitted through sexual contact. Endogenous infection (A) refers to infections originating from the body's own flora, which is not the case here. Contact infection (C) typically involves direct physical contact or fomite transmission, which is less likely in this scenario. Vector-borne transmission (D) involves transmission through vectors like mosquitoes or ticks, which is not relevant in this case.
The term “infectious process†means “all biological processes carried out after…â€
- A. The attachment and penetration of microbes into the microorganism
- B. The attachment and penetration of microbes into the microorganisms regardless of whether or not there is clinical manifestation
- C. The penetration of microbes into the macroorganism and always manifest clinically
- D. No correct answer
Correct Answer: B
Rationale: The correct answer is B because the term "infectious process" refers to all biological processes that occur after the attachment and penetration of microbes into the host organism, regardless of whether there are clinical manifestations. This includes the colonization, multiplication, and spread of the microorganisms within the host.
Explanation:
A: Incorrect because it only mentions the attachment and penetration of microbes into the microorganism, missing the subsequent processes.
C: Incorrect because it is too specific, stating that the penetration of microbes always manifests clinically, which is not always the case.
D: Incorrect because there is a correct answer, which is B, as explained above.